Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 14/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 14/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | CFB | P00751 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564280 | 0.89 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL12883104 | 0.84 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CADRA1AGMNN | |
| SCHEMBL10556098 | 0.82 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1AGMNN | |
| SCHEMBL10555827 | 0.74 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL10554892 | 0.74 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL10680232 | 0.74 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1AGMNN | |
| SCHEMBL1723548 | 0.73 | ADRA2B (0.84) | ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL6897370 | 0.71 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CADRA1AGMNN | |
| SCHEMBL1724062 | 0.71 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1ATSHR | |
| SCHEMBL9619248 | 0.69 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1AGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861789-A | Dihydro-indene-amine-dihydrooxazoles | BEECHAM GROUP PLC (GB) | 1989-08-29 | — | — | US | claimed |
| EP-0251453-A2 | Substituted amino-dihydrooxazoles, -thiazoles and -imidazoles, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-01-07 | — | — | EP | claimed |
| WO-2023185811-A1 | NOVEL HETEROCYCLIC COMPOUND | 首药控股(北京)股份有限公司 | 2023-10-05 | — | — | WO | disclosed |
| US-20210309642-A1 | Process for Manufacture of (S)-N-(3-((2-((4-((1-acetylpyrrolidin-3-yl)(methyl)amino)phenyl)amino)-5-methoxypyrimidin-4-yl)oxy)phenyl)acrylamide, and Formulations Thereof | ACEA Therapeutics, Inc. (US) | 2021-10-07 | — | — | US | disclosed |
| US-20100298138-A1 | Aminoazoline and Urea Derivatives for Combating Animal Pests | BASF SE (DE) | 2010-11-25 | — | — | US | disclosed |
| CN-101677552-A | The Aminoazoline and the urea derivative of control animal pest | BASF SE | 2010-03-24 | — | — | CN | disclosed |
| EP-2120576-A2 | AMINOAZOLINE AND UREA DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008145615-A2 | AMINOAZOLINE AND UREA DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008135181-A2 | INSECTICIDAL SUBSTITUTED 2-AMINOINDANES | BAYER CROPSCIENCE AG (DE) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008135181-A2 | INSECTICIDAL SUBSTITUTED 2-AMINOINDANES | BAYER CROPSCIENCE AG (DE) | 2008-11-13 | — | — | WO | disclosed |
| EP-1988080-A1 | Insecticidal substituted 2-aminoindanes | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1988080-A1 | Insecticidal substituted 2-aminoindanes | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| US-4861879-A | VAGINAL FUNGICIDE | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-08-29 | — | — | US | disclosed |
| US-4861789-A | Dihydro-indene-amine-dihydrooxazoles | BEECHAM GROUP PLC (GB) | 1989-08-29 | — | — | US | disclosed |
| US-4803268-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0251453-A2 | Substituted amino-dihydrooxazoles, -thiazoles and -imidazoles, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298138-A1 | Aminoazoline and Urea Derivatives for Combating Animal Pests | AADAT, INMT, SLC14A1 | ADRA2A 2376/4885ADRA2B 1308/4885ADRA2C 988/4885 |
| US-20210309642-A1 | Process for Manufacture of (S)-N-(3-((2-((4-((1-acetylpyrrolidin-3-yl)(methyl)amino)phenyl)amino)-5-methoxypyrimidin-4-yl)oxy)phenyl)acrylamide, and Formulations Thereof | BMX, ITK, BLK | ADRA2A 3825/4885ADRA2B 3921/4885ADRA2C 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.