SCHEMBL375283

SCHEMBL375283

CCOC(OCC)[SiH2]CCS

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375562 0.86 THRB (0.32) THRBLMNA
SCHEMBL29211233 0.84 THRB (0.31) THRB
SCHEMBL4106515 0.84 THRB (0.31) THRB
SCHEMBL331066 0.84 THRB (0.42) THRBLMNA
SCHEMBL15524147 0.82
SCHEMBL375770 0.79 THRB (0.45) THRBLMNA
SCHEMBL704023 0.79 THRB (0.38) THRBLMNA
SCHEMBL557200 0.79 THRB (0.38) THRBLMNA
SCHEMBL646412 0.79 THRB (0.38) THRBLMNA
SCHEMBL6007776 0.77 THRB (0.36) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795499-B Process for producing alkoxysilyl group-containing thiocarboxylate 迈图高新材料公司 2024-03-19 CN claimed
EP-3962917-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS Momentive Performance Materials Inc. (US) 2022-03-09 EP claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN claimed
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-02-16 US claimed
WO-2020223068-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-11-05 WO claimed
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. 2020-11-05 US claimed
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US claimed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 US claimed
US-12139635-B2 Coatings for waterproofing electronic components HENKEL AG & CO. KGAA (DE) 2024-11-12 US disclosed
CN-113795499-B Process for producing alkoxysilyl group-containing thiocarboxylate 迈图高新材料公司 2024-03-19 CN disclosed
US-11613709-B2 Method for making hydrodesulfurization catalyst including calcination KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-03-28 US disclosed
US-11584892-B2 Autoclave method for hydrothermal preparation of a hydrodesulfurization catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-02-21 US disclosed
US-11560522-B2 Method of making a hydrodesulfurization catalyst with a structural directing surfactant KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-01-24 US disclosed
US-11549071-B2 Catalyst preparation method using an acidified structural directing surfactant KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-01-10 US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 EP disclosed
US-4524169-A THERMOPLASTIC RUBBER, SILICATE FILLER, AND AN ORGANOSILICON COMPOUND DEGUSSA AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
US-4278587-A HALOALKYLSILANE DEGUSSA AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST THRB 4696/4885LMNA 3513/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C THRB 4640/4885LMNA 4012/4885
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters TST, MPST, APEH THRB 3078/4885LMNA 4244/4885
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS TST, MPST, APEH THRB 3078/4885LMNA 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.