SCHEMBL375654

SCHEMBL375654

Cc1cc(S(=O)(=O)[O-])c(N/N=C2\C(=O)C(C(=O)[O-])=Cc3ccccc32)cc1Cl.[Ca+2]

nearest known ligand 0.35

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY4 P51582 7/20 0.35
NFKB1 P19838 1/20 0.32
P2RY2 P41231 4/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPT P10636 3/20 0.31
L3MBTL1 Q9Y468 3/20 0.31
HPGD P15428 2/20 0.31
MAPK1 P28482 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
LMNA P02545 2/20 0.31
APAF1 O14727 1/20 0.31
TP53 P04637 1/20 0.31
HTT P42858 1/20 0.31
MCL1 Q07820 1/20 0.31
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
MEN1 O00255 3/20 0.30
KMT2A Q03164 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436773 0.98 P2RY4 (0.35) P2RY4NFKB1P2RY2ALDH1A1MAPT
SCHEMBL571587 0.98 P2RY4 (0.35) P2RY4NFKB1P2RY2ALDH1A1MAPT
SCHEMBL341149 0.98 P2RY4 (0.37) P2RY4NFKB1P2RY2ALDH1A1MAPT
SCHEMBL5410698 0.96 P2RY4 (0.35) P2RY4NFKB1P2RY2ALDH1A1MAPT
SCHEMBL21436337 0.94 P2RY4 (0.37) P2RY4NFKB1P2RY2ALDH1A1MAPT
SCHEMBL21436616 0.94 P2RY4 (0.35) P2RY4NFKB1P2RY2ALDH1A1MAPT
SCHEMBL21436523 0.91 P2RY4 (0.32) P2RY4ALDH1A1MAPTL3MBTL1HPGD
SCHEMBL341670 0.85 P2RY4 (0.36) P2RY4P2RY2ALDH1A1MAPTL3MBTL1
SCHEMBL21436596 0.85 P2RY4 (0.35) P2RY4P2RY2MEN1KMT2ACDK2
SCHEMBL21436561 0.85 P2RY4 (0.33) P2RY4P2RY2MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144182-A1 SEED COATING COMPOSITION CRODA, INC. (US) 2026-05-28 US disclosed
EP-4709167-A1 SEED COATING BINDER Croda International PLC (GB) 2026-03-18 EP disclosed
WO-2026041607-A1 AZIRIDINYL-FUNCTIONAL ORGANIC COMPOUNDS COVESTRO (NETHERLANDS) B.V. (NL) 2026-02-26 WO disclosed
US-20260026426-A1 METHOD FOR COATING SEEDS LAMBERTI SPA (IT) 2026-01-29 US disclosed
EP-4684638-A1 METHOD FOR COATING SEEDS Lamberti SPA (IT) 2026-01-28 EP disclosed
EP-4658071-A1 FILM AND SEED COATING DISPERSANT Croda International PLC (GB) 2025-12-10 EP disclosed
EP-4637349-A1 CONTROLLED RELEASE OF ENCAPSULATED AGROCHEMICALS BY BIODEGRADATION Xampla Limited (GB) 2025-10-29 EP disclosed
EP-4611542-A1 SEED COATING COMPOSITION Croda, Inc. (US) 2025-09-10 EP disclosed
WO-2025127105-A1 COATING COMPOSITION FOR AGRICULTURAL USE, AND COATED SEED 株式会社クラレ 2025-06-19 WO disclosed
CN-120152618-A Seed coating composition 禾大公司 2025-06-13 CN disclosed
WO-2016039623-A1 USE OF ALDEHYDES FOR IMPROVING PLANT GROWTH INCOTEC HOLDING B.V. (NL) 2016-03-17 WO disclosed
WO-2015193239-A1 TREATMENT FOR PLANT SEEDS INCOTEC HOLDING B.V. (NL) 2015-12-23 WO disclosed
WO-2015192923-A1 TREATMENT FOR PLANT SEEDS INCOTEC HOLDING B.V. (NL) 2015-12-23 WO disclosed
EP-2408290-B1 SEED COATING COMPOSITION INCOTEC EUROP B V (NL) 2015-05-27 EP disclosed
US-20120065060-A1 SEED COATING COMPOSITION INCOTEC EUROPE B. V. (NL) 2012-03-15 US disclosed
EP-2408290-A1 SEED COATING COMPOSITION Incotec International B.V. (NL) 2012-01-25 EP disclosed
WO-2011028115-A1 CONTROLLED SEED WETTING INCOTEC INTERNATIONAL B.V. (NL) 2011-03-10 WO disclosed
WO-2010107312-A1 SEED COATING COMPOSITION INCOTEC INTERNATIONAL B.V. (NL) 2010-09-23 WO disclosed
EP-2229808-A1 Seed coating composition Incotec International B.V. (NL) 2010-09-22 EP disclosed
US-20050064128-A1 Method and apparatus for forming building panels and components which simulate man-made tiles and natural stones LANE JOHN CLINTON (US) 2005-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260026426-A1 METHOD FOR COATING SEEDS SDC1, SDC2, ALG1 P2RY4 4224/4885NFKB1 2964/4885P2RY2 3769/4885
US-20260144182-A1 SEED COATING COMPOSITION CUTA, PLIN3, ACACB P2RY4 4214/4885NFKB1 4394/4885P2RY2 3892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.