Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 12/20 | 0.37 |
| ▸ | P2RY12 known ✓ | Q9H244 | 3/20 | 0.33 |
| ▸ | P2RY2 known ✓ | P41231 | 7/20 | 0.33 |
| ▸ | P2RY1 known ✓ | P47900 | 2/20 | 0.32 |
| ▸ | P2RY6 known ✓ | Q15077 | 1/20 | 0.32 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5410698 | 0.98 | P2RY4 (0.35) | P2RY4P2RY12NFKB1P2RY2CDK2 | |
| SCHEMBL21436616 | 0.98 | P2RY4 (0.35) | P2RY4P2RY12NFKB1P2RY2CDK2 | |
| SCHEMBL341149 | 0.96 | P2RY4 (0.37) | P2RY4P2RY12NFKB1P2RY2CDK2 | |
| SCHEMBL375654 | 0.94 | P2RY4 (0.35) | P2RY4NFKB1P2RY2CDK2P2RY1 | |
| SCHEMBL21436773 | 0.94 | P2RY4 (0.35) | P2RY4NFKB1P2RY2CDK2P2RY1 | |
| SCHEMBL571587 | 0.94 | P2RY4 (0.35) | P2RY4NFKB1P2RY2CDK2P2RY1 | |
| SCHEMBL21436596 | 0.89 | P2RY4 (0.35) | P2RY4P2RY12P2RY2CDK2MEN1 | |
| SCHEMBL21436523 | 0.89 | P2RY4 (0.32) | P2RY4ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL21436561 | 0.87 | P2RY4 (0.33) | P2RY4P2RY12P2RY2MEN1POLB | |
| SCHEMBL341437 | 0.85 | P2RY4 (0.38) | P2RY4P2RY12P2RY2CDK2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | HFC PRESTIGE SERVICE GERMINY GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-4171500-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | Wella Germany GmbH (DE) | 2023-05-03 | — | — | EP | disclosed |
| US-11324688-B2 | Bicomponent composition | WELLA INTERNATIONAL OPERATIONS SWI (CH) | 2022-05-10 | — | — | US | disclosed |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2022-02-24 | — | — | US | disclosed |
| US-20220016017-A1 | COLOR COATINGS WITH DOWNSTREAM FEATURES | HFC PRESTIGE SERVICE GERMANY GMBH (DE) | 2022-01-20 | — | — | US | disclosed |
| WO-2022002983-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | HFC PRESTIGE SERVICE GERMANY GMBH (DE) | 2022-01-06 | — | — | WO | disclosed |
| EP-3890683-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-10-13 | — | — | EP | disclosed |
| US-20210290519-A1 | MULTICOMPONENT SILICONE COMPOSITION | WELLA INT OPERATIONS SWITZERLAND SARL (CH) | 2021-09-23 | — | — | US | disclosed |
| US-20210290518-A1 | MULTICOMPONENT COMPOSITION | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2021-09-23 | — | — | US | disclosed |
| US-20210145726-A1 | BICOMPONENT COMPOSITION | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2021-05-20 | — | — | US | disclosed |
| EP-3817710-A1 | MULTICOMPONENT SILICONE COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-05-12 | — | — | EP | disclosed |
| EP-3817825-A1 | MULTICOMPONENT PUR COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-05-12 | — | — | EP | disclosed |
| EP-3787753-A1 | MULTICOMPONENT COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-03-10 | — | — | EP | disclosed |
| EP-3773922-A1 | BICOMPONENT COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-02-17 | — | — | EP | disclosed |
| WO-2020114647-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020007510-A1 | MULTICOMPONENT PUR COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2020-01-09 | — | — | WO | disclosed |
| WO-2020007511-A1 | MULTICOMPONENT SILICONE COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2020-01-09 | — | — | WO | disclosed |
| WO-2019192916-A1 | BICOMPONENT COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016017-A1 | COLOR COATINGS WITH DOWNSTREAM FEATURES | KRT18, ITGA5, FLNA | P2RY4 3803/4885P2RY12 4091/4885P2RY2 3753/4885 |
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | KRT18, MKI67, IK | P2RY4 4027/4885P2RY12 4452/4885P2RY2 4412/4885 |
| US-20210290519-A1 | MULTICOMPONENT SILICONE COMPOSITION | CUTA, CD99, PLOD3 | P2RY4 3665/4885P2RY12 3969/4885P2RY2 3818/4885 |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | KRT18, PRKDC, VIM | P2RY4 4672/4885P2RY12 4739/4885P2RY2 4696/4885 |
| US-11324688-B2 | Bicomponent composition | KRT18, EXOSC10, EXOSC9 | P2RY4 3269/4885P2RY12 3317/4885P2RY2 2950/4885 |
| US-20210290518-A1 | MULTICOMPONENT COMPOSITION | KRT18, INCENP, IK | P2RY4 2954/4885P2RY12 3594/4885P2RY2 3510/4885 |
| US-20210145726-A1 | BICOMPONENT COMPOSITION | KRT18, EXOSC10, EXOSC9 | P2RY4 3269/4885P2RY12 3317/4885P2RY2 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.