Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031863 | 0.90 | L3MBTL1 (0.50) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL10415038 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL1156528 | 0.84 | KMT2A (0.69) | ALDH1A1KMT2ATDP1MEN1NPC1 | |
| SCHEMBL8535189 | 0.83 | KMT2A (0.68) | ALDH1A1KMT2ATDP1MEN1NPC1 | |
| SCHEMBL3822474 | 0.82 | L3MBTL1 (0.58) | ALDH1A1KMT2AMEN1NPC1LMNA | |
| SCHEMBL26757664 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL22507577 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7434246 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL10708405 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL15441486 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754252-B2 | Asymmetric cyclization processes using unsaturated nitro compounds | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-06-17 | — | — | US | disclosed |
| US-20130096338-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-04-18 | — | — | US | disclosed |
| US-8222274-B2 | Pyrrole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-1988075-B1 | PYRROLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-20100298576-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-11-25 | — | — | US | disclosed |
| US-20090036421-A1 | Pyrrole Derivative or Salt Thereof | ASTELLAS PHARMA INC (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1988075-A1 | PYRROLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036421-A1 | Pyrrole Derivative or Salt Thereof | HTR7, HTR2B, SSTR5 | ALDH1A1 4209/4885KMT2A 4232/4885TDP1 3645/4885 |
| US-20130096338-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NQO1, COASY, NOS2 | ALDH1A1 2383/4885KMT2A 3541/4885TDP1 3674/4885 |
| US-20100298576-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NQO1, COASY, NOS2 | ALDH1A1 2383/4885KMT2A 3541/4885TDP1 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.