Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014923 | 0.92 | KMT2A (0.75) | KMT2ANPC1MEN1POLBNPSR1 | |
| SCHEMBL10830586 | 0.90 | KMT2A (0.73) | KMT2ANPC1MEN1POLBNPSR1 | |
| SCHEMBL973673 | 0.87 | KMT2A (0.69) | KMT2ANPC1MEN1POLBNPSR1 | |
| SCHEMBL2070001 | 0.86 | KMT2A (0.67) | KMT2ANPC1MEN1POLBNPSR1 | |
| SCHEMBL8535189 | 0.85 | KMT2A (0.68) | KMT2ANPC1MEN1POLBNPSR1 | |
| SCHEMBL13082074 | 0.85 | KMT2A (0.50) | KMT2ANPC1MEN1POLBNPSR1 | |
| SCHEMBL2884408 | 0.84 | L3MBTL1 (0.50) | KMT2ANPC1MEN1POLBALDH1A1 | |
| SCHEMBL3032065 | 0.84 | KMT2A (0.49) | KMT2ANPC1MEN1NPSR1TDP1 | |
| SCHEMBL1156727 | 0.84 | KMT2A (0.49) | KMT2ANPC1MEN1POLBNPSR1 | |
| SCHEMBL375694 | 0.84 | ALDH1A1 (0.53) | KMT2ANPC1MEN1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3018125-B1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | SHIN NIPPON BIOMEDICAL LABORATORIES LTD (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-10308605-B2 | Proton pump inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-06-04 | — | — | US | disclosed |
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | THE UNIVERSITY OF UTAH | 2017-03-09 | — | — | US | disclosed |
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | THE UNIVERSITY OF UTAH | 2017-03-09 | — | — | US | disclosed |
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | THE UNIVERSITY OF UTAH | 2017-03-09 | — | — | US | disclosed |
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
| US-9340500-B2 | Aromatic heterocyclic derivative having TRPV4-inhibiting activity | SHIONOGI & CO., LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| US-9340500-B2 | Aromatic heterocyclic derivative having TRPV4-inhibiting activity | SHIONOGI & CO., LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| EP-3018125-A1 | NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR | Shin Nippon Biomedical Laboratories, Ltd. (JP) | 2016-05-11 | — | — | EP | disclosed |
| WO-2004069227-A1 | AQUEOUS DISPERSION COMPRISING STABLE NANOPARTICLES OF A WATER-INSOLUBLE PYRROLE CARBOXAMIDE AND EXCIPIENT LIKE MIDDLE CHAIN TRIGLYCERIDES | ASTRAZENECA AB (SE) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004058249-A1 | 1,5-DIARYL-PYRROLE-3-CARBOXAMIDE DERIVATIVES AND THEIR USE AS CANNABINOID RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2004-07-15 | — | — | WO | disclosed |
| US-6569890-B2 | Antiinflamamtory agents | ICOS CORPORATION | 2003-05-27 | — | — | US | disclosed |
| US-20030013754-A1 | Cyclic AMP-specific phosphodiesterase inhibitors | ICOS CORPORATION | 2003-01-16 | — | — | US | disclosed |
| EP-1244620-A1 | CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITORS | ICOS CORPORATION (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6372777-B1 | ENZYME INHIBITORS TREATMENT OF INFLAMMATORY DISEASES AND OTHER DISEASES INVOLVING ELEVATED LEVELS OF CYTOKINES, AS WELL AS CENTRAL NERVOUS SYSTEM (CNS) DISORDERS, | ICOS CORPORATION | 2002-04-16 | — | — | US | disclosed |
| WO-2001047880-A1 | CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITORS | ICOS CORPORATION (US) | 2001-07-05 | — | — | WO | disclosed |
| US-5114462-A | Herbicides as plant growth regulators, phenoxypropionic acid esters and derivatives | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5078780-A | Plant safening agents for use with herbicides | CIBA-GEIGY CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| US-4944790-A | PLANT SAFENING AGENTS FOR USE WITH CERTAIN HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013754-A1 | Cyclic AMP-specific phosphodiesterase inhibitors | PDE4A, PDE4B, PDE4C | KMT2A 3995/4885NPC1 4258/4885MEN1 3232/4885 |
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SLCO1B3, SLC22A8, SLC10A6 | KMT2A 3316/4885NPC1 135/4885MEN1 2566/4885 |
| US-10308605-B2 | Proton pump inhibitors | HRH2, HRH4, HRH1 | KMT2A 2262/4885NPC1 596/4885MEN1 1854/4885 |
| US-20170065602-A1 | COMPOUNDS WITH TRPV4 ACTIVITY, COMPOSITIONS AND ASSOCIATED METHODS THEREOF | TRPV4, TRPV3, TRPV2 | KMT2A 4684/4885NPC1 470/4885MEN1 4076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.