SCHEMBL375869

SCHEMBL375869

CCCCO[Si](C)(CCCS)OCCCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14191177 0.94
SCHEMBL4539608 0.92 THRB (0.32)
SCHEMBL375555 0.92 THRB (0.32)
SCHEMBL375528 0.89
SCHEMBL28805966 0.86 ADRB2 (0.38) ADRB2ADRB1ADRB3
SCHEMBL706695 0.86 ADRB2 (0.38) ADRB2ADRB1ADRB3
SCHEMBL705364 0.86 ADRB2 (0.38) ADRB2ADRB1ADRB3
SCHEMBL703594 0.84 ADRB2 (0.39) ADRB2ADRB1ADRB3
SCHEMBL375539 0.83 ADRB2 (0.32) ADRB2ADRB1ADRB3
SCHEMBL11332073 0.82 THRB (0.38) ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115991878-B Silicone resin, modified rubber, rubber-plastic composite material, preparation method thereof and application of silicone resin, modified rubber and rubber-plastic composite material in tire carcass rubber 广东粤港澳大湾区黄埔材料研究院 2023-07-07 CN claimed
CN-115991878-A Silicone resin, modified rubber, rubber-plastic composite material, preparation method thereof and application of silicone resin, modified rubber and rubber-plastic composite material in tire carcass rubber 广东粤港澳大湾区黄埔材料研究院 2023-04-21 CN claimed
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US claimed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 US claimed
US-12617238-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
US-12545055-B2 Tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-02-10 US disclosed
US-12515477-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-01-06 US disclosed
US-12515483-B2 Tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-01-06 US disclosed
US-12508840-B2 Tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-12-30 US disclosed
US-12502912-B2 Tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-12-23 US disclosed
EP-4112334-B1 TIRE SUMITOMO RUBBER IND (JP) 2025-08-20 EP disclosed
EP-4600051-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2025-08-13 EP disclosed
US-20060035129-A1 Proton conducting membrane, method for producing the same and fuel cell using the same SEKISUI CHEMICAL CO., LTD. (JP) 2006-02-16 US disclosed
US-6995280-B2 Process for preparing (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-02-07 US disclosed
EP-1619692-A1 PROTON-CONDUCTIVE FILM, PROCESS FOR PRODUCING THE SAME, AND FUEL CELL EMPOLYING THE PROTON-CONDUCTIVE FILM SEKISUI CHEMICAL CO., LTD. (JP) 2006-01-25 EP disclosed
EP-1592025-A1 PROTON CONDUCTING FILM, METHOD FOR PRODUCING THE SAME, AND FUEL CELL USING THE SAME SEKISUI CHEMICAL CO., LTD. (JP) 2005-11-02 EP disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST ADRB2 1933/4885ADRB1 2168/4885ADRB3 1427/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C ADRB2 1713/4885ADRB1 1589/4885ADRB3 1162/4885
US-12545055-B2 Tire RAE1, TRAFD1, POT1 ADRB2 983/4885ADRB1 1111/4885ADRB3 2556/4885
US-12508840-B2 Tire LBR, CCT4, TRRAP ADRB2 842/4885ADRB1 779/4885ADRB3 2001/4885
US-12617238-B2 Pneumatic tire CCT4, CCT7, CCNE2 ADRB2 948/4885ADRB1 1232/4885ADRB3 3294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.