Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11700751 | 0.98 | ALDH1A1 (0.60) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2909398 | 0.86 | PDXK (0.61) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4016022 | 0.86 | KDM4E (0.61) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1645737 | 0.86 | PDXK (0.56) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11449347 | 0.81 | KDM4E (0.56) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4558720 | 0.81 | PDXK (0.51) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3900653 | 0.80 | PDXK (0.50) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5500541 | 0.79 | PDXK (0.49) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| Sulfuric Acid SCHEMBL10628805 | 0.79 | LMNA (0.49) | PDXKALDH1A1KDM4EHPGDHSD17B10 | |
| Pyridoxine SCHEMBL2322958 | 0.77 | HPGD (1.00) | PDXKALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431712-B2 | Methods for the synthesis of pyridoxamine | NEPHROGENEX, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100305162-A1 | Methods for the Synthesis of Pyridoxamine | NEPHROGENEX, INC | 2010-12-02 | — | — | US | disclosed |
| US-20070161678-A1 | Methods for the synthesis of pyridoxamine | BIOSTRATUM, INC. | 2007-07-12 | — | — | US | disclosed |
| US-7214799-B2 | Methods for the synthesis of pyridoxamine | BIOSTRATUM, INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7147859-B2 | Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers | LABORATORIOS BIOSINTETICA LTDA. (BR) | 2006-12-12 | — | — | US | disclosed |
| US-20060039932-A1 | Application of phytosteroids (and isomers thereof), folic acid, cyanocobalamine and pyridoxine in dietetic (alimentary) fibers | LABORATORIOS BIOSINTETICA LTDA. (BR) | 2006-02-23 | — | — | US | disclosed |
| CN-1715413-A | Corynebacterium glutamicum genes encoding metabolic pathway proteins | BASF AG (DE) | 2006-01-04 | — | — | CN | disclosed |
| US-20050272781-A1 | Methods for the synthesis of pyridoxamine | PRAETEGO, INC. | 2005-12-08 | — | — | US | disclosed |
| WO-2005077902-A2 | METHODS FOR THE SYNTHESIS OF PYRIDOXAMINE | BIOSTRATUM, INC. (US) | 2005-08-25 | — | — | WO | disclosed |
| US-20030133965-A1 | Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers | LABORATORIOS BIOSINTETICA LTDA. (BR) | 2003-07-17 | — | — | US | disclosed |
| US-20020018811-A1 | Application of phytosteroids(and isomers thereof), folic acid, cyanocobalamine and pyridoxine in dietetic (alimentary) fibers | LABORATORIOS BIOSINTETICA LTDA. (BR) | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272781-A1 | Methods for the synthesis of pyridoxamine | AGER, PDXK, PNPO | PDXK 2/4885ALDH1A1 341/4885KDM4E 239/4885 |
| US-20100305162-A1 | Methods for the Synthesis of Pyridoxamine | AGER, PDXK, PNPO | PDXK 2/4885ALDH1A1 356/4885KDM4E 214/4885 |
| US-20020018811-A1 | Application of phytosteroids(and isomers thereof), folic acid, cyanocobalamine and pyridoxine in dietetic (alimentary) fibers | PLPBP, FOLR2, FOLR1 | PDXK 70/4885ALDH1A1 1896/4885KDM4E 3645/4885 |
| US-20060039932-A1 | Application of phytosteroids (and isomers thereof), folic acid, cyanocobalamine and pyridoxine in dietetic (alimentary) fibers | PLPBP, FOLR2, FOLR1 | PDXK 86/4885ALDH1A1 1752/4885KDM4E 3512/4885 |
| US-20030133965-A1 | Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers | PLPBP, FOLR2, FOLR1 | PDXK 83/4885ALDH1A1 1919/4885KDM4E 4274/4885 |
| US-20070161678-A1 | Methods for the synthesis of pyridoxamine | AGER, PDXK, PNPO | PDXK 2/4885ALDH1A1 335/4885KDM4E 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.