Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638818 | 0.80 | PDXK (0.62) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3761208 | 0.80 | PDXK (0.62) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11700751 | 0.78 | ALDH1A1 (0.60) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4577011 | 0.75 | KDM4E (0.67) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4016022 | 0.75 | KDM4E (0.61) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1645737 | 0.75 | PDXK (0.56) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2909398 | 0.75 | PDXK (0.61) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| Pyridoxine SCHEMBL43879 | 0.75 | KDM4E (0.83) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| Pyridoxine SCHEMBL29004449 | 0.75 | KDM4E (0.83) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| Pyridoxine SCHEMBL1545934 | 0.73 | KDM4E (0.80) | PDXKKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012167243-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR OBESITY | B & P COMPANY, INC. (US) | 2012-12-06 | — | — | WO | claimed |
| WO-2012167243-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR OBESITY | B & P COMPANY, INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| EP-1703911-A4 | COMBINATION THERAPIES EMPLOYING A COMPOSITION COMPRISING A HMG COA REDUCTASE INHIBITOR AND A VITAMIN B6 RELATED COMPOUND | MEDICURE INT INC (BB) | 2009-03-18 | — | — | EP | disclosed |
| US-20080311099-A1 | Pyridoxal-5-Phosphate and Related Compounds in Combination With Therapeutic Cardiovascular Compounds for Treating Angina | MEDICURE INTERNATIONAL INC. | 2008-12-18 | — | — | US | disclosed |
| US-20080311099-A1 | Pyridoxal-5-Phosphate and Related Compounds in Combination With Therapeutic Cardiovascular Compounds for Treating Angina | MEDICURE INTERNATIONAL INC. | 2008-12-18 | — | — | US | disclosed |
| US-7442689-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2008-10-28 | — | — | US | disclosed |
| US-7442689-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2008-10-28 | — | — | US | disclosed |
| US-20080214504-A1 | Vitamin B6 Related Compounds and Methods for Recovery From Trauma | MEDICURE INTERNATIONAL INC. (BB) | 2008-09-04 | — | — | US | disclosed |
| US-20080139511-A1 | Combination Therapies Employing Ace Inhibitors and Uses Thereof for the Treatment of Diabetic Disorders | MEDICURE INTERNATIONAL INC. (BB) | 2008-06-12 | — | — | US | disclosed |
| US-7375112-B2 | Compounds and methods for regulating triglyceride levels | MEDICURE INTERNATIONAL INC. (BB) | 2008-05-20 | — | — | US | disclosed |
| EP-1278526-A2 | TREATMENT OF CEREBROVASCULAR DISEASE | Medicure International Inc. (BB) | 2003-01-29 | — | — | EP | disclosed |
| EP-1268498-A1 | CARDIOPROTECTIVE PHOSPHONATES AND MALONATES | Medicure International Inc. (BB) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072309-A3 | TREATMENT OF CEREBROVASCULAR DISEASE | MEDICURE INT INC (BB) | 2002-06-13 | — | — | WO | disclosed |
| US-20020010158-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (CA) | 2002-01-24 | — | — | US | disclosed |
| US-20020010158-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (CA) | 2002-01-24 | — | — | US | disclosed |
| US-20010056081-A1 | Treatment of cerebrovascular disease | MEDICURE INTERNATIONAL INC. (CA) | 2001-12-27 | — | — | US | disclosed |
| US-20010056081-A1 | Treatment of cerebrovascular disease | MEDICURE INTERNATIONAL INC. (CA) | 2001-12-27 | — | — | US | disclosed |
| WO-2001072309-A2 | TREATMENT OF CEREBROVASCULAR DISEASE | MEDICURE INTERNATIONAL INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072309-A2 | TREATMENT OF CEREBROVASCULAR DISEASE | MEDICURE INTERNATIONAL INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001064692-A1 | CARDIOPROTECTIVE PHOSPHONATES AND MALONATES | MEDICURE INTERNATIONAL INC. (BB) | 2001-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311099-A1 | Pyridoxal-5-Phosphate and Related Compounds in Combination With Therapeutic Cardiovascular Compounds for Treating Angina | ALOX5, PNPO, KCNMB1 | PDXK 129/4885KDM4E 1392/4885ALDH1A1 1179/4885 |
| US-20020010158-A1 | Cardioprotective phosphonates and malonates | PDXK, PHOSPHO1, PNPO | PDXK 1/4885KDM4E 519/4885ALDH1A1 2080/4885 |
| US-20080214504-A1 | Vitamin B6 Related Compounds and Methods for Recovery From Trauma | PLPBP, PNPO, SERPINB6 | PDXK 4/4885KDM4E 1298/4885ALDH1A1 1021/4885 |
| US-20010056081-A1 | Treatment of cerebrovascular disease | PNPO, PLPBP, VNN1 | PDXK 4/4885KDM4E 1422/4885ALDH1A1 1352/4885 |
| US-20080139511-A1 | Combination Therapies Employing Ace Inhibitors and Uses Thereof for the Treatment of Diabetic Disorders | ACE, ACE2, REN | PDXK 10/4885KDM4E 2342/4885ALDH1A1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.