Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772602 | 0.88 | NPC1 (0.53) | TP53ALDH1A1KDM4EGAAHPGD | |
| N-Benzylmethylamine SCHEMBL5556336 | 0.84 | NCF1 (0.50) | HTR1AHTR7KMT2AKDM4E | |
| SCHEMBL5189076 | 0.80 | HTR1A (0.45) | HTR1AHTR7ALDH1A1KMT2AKDM4E | |
| SCHEMBL3762994 | 0.77 | NPC1 (0.51) | TP53ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL3763647 | 0.76 | HDAC3 (0.50) | KMT2AMEN1 | |
| SCHEMBL13684982 | 0.76 | SRC (0.47) | TP53ALDH1A1L3MBTL1HPGDRAB9A | |
| SCHEMBL22145190 | 0.74 | ALDH1A1 (0.76) | HTR1AHTR7ALDH1A1KMT2AMEN1 | |
| SCHEMBL3762346 | 0.73 | HRH3 (0.50) | ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3761869 | 0.72 | GAA (0.50) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL22145587 | 0.69 | SIGMAR1 (0.60) | TP53ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842812-B2 | Substituted 5-aminomethy1-1H-pyrrole-2-carboxylic acid amides | GRUENENTHAL GMBH (DE) | 2010-11-30 | — | — | US | disclosed |
| US-20070135494-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides | GRUENENTHAL GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135494-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides | AVPR2, GPR119, AVPR1B | TP53 4718/4885HTR1A 749/4885HTR7 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.