Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761968 | 0.84 | TP53 (0.49) | HTR1AHTR7KMT2AKDM4E | |
| SCHEMBL3772602 | 0.77 | NPC1 (0.53) | CYP2D6KDM4EMAPTHRH3 | |
| SCHEMBL13684982 | 0.75 | SRC (0.47) | HIF1ACYP3A4HRH3 | |
| SCHEMBL5189076 | 0.74 | HTR1A (0.45) | DPP7HTR1AHTR7KMT2AKDM4E | |
| SCHEMBL3762346 | 0.72 | HRH3 (0.50) | KDM4EHRH3 | |
| SCHEMBL3757509 | 0.70 | MEN1 (0.54) | DPP7CYP2C9KMT2AKDM4EMAPT | |
| SCHEMBL1934394 | 0.69 | NCF1 (1.00) | NCF1CYP2D6KMT2AKDM4EHRH3 | |
| SCHEMBL5187264 | 0.68 | BCHE (0.46) | KMT2AKDM4EHRH3 | |
| SCHEMBL4657901 | 0.68 | HRH3 (0.50) | NCF1KDM4EHRH3 | |
| N-Benzylmethylamine SCHEMBL28296920 | 0.68 | MAPT (0.77) | CYP2D6CYP2C9KMT2AKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135494-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides | GRUENENTHAL GMBH (DE) | 2007-06-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135494-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides | AVPR2, GPR119, AVPR1B | NCF1 4825/4885DPP7 403/4885HTR1A 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.