Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Methylene Chloride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL542397 | 1.00 | ALDH1A1 (0.80) | — | |
| Methylene Chloride SCHEMBL4866938 | 1.00 | ALDH1A1 (0.80) | — | |
| Methylene Chloride SCHEMBL11137267 | 1.00 | ALDH1A1 (0.80) | — | |
| Methylene Chloride SCHEMBL7572150 | 1.00 | ALDH1A1 (0.80) | — | |
| Methylene Chloride SCHEMBL4859310 | 1.00 | ALDH1A1 (0.80) | — | |
| Methylene Chloride SCHEMBL20539491 | 1.00 | — | — | |
| Methylene Chloride SCHEMBL7299292 | 1.00 | — | — | |
| Methylene Chloride SCHEMBL542380 | 1.00 | ALDH1A1 (0.80) | — | |
| Methylene Chloride SCHEMBL9259939 | 1.00 | ALDH1A1 (0.80) | — | |
| Methylene Chloride SCHEMBL2983 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3253 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119468-A1 | TREATMENT METHOD FOR DICHLOROMETHANE IN ACESULFAME PRODUCTION | 安徽金禾实业股份有限公司 | 2024-06-13 | — | — | WO | claimed |
| CN-118027122-A | New anti-aging active iridoid component in eucommia ulmoides leaves as well as preparation method and application thereof | 贵州省天然产物研究中心 | 2024-05-14 | — | — | CN | claimed |
| CN-115304661-B | Cyclic peptide compound and application thereof | 西南民族大学 | 2024-03-15 | — | — | CN | claimed |
| CN-116332720-B | Recovery and purification method of waste solvent | 四川熔增环保科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-116173159-B | Zedoary turmeric oil sulfonate, and preparation method and application thereof | 北京中医药大学东直门医院 | 2024-02-02 | — | — | CN | claimed |
| CN-117438133-A | Low-temperature sintered silver paste and preparation method thereof | 长沙先进电子材料工业技术研究院有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-116332720-A | Recovery and purification method of waste solvent | 四川熔增环保科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116234789-A | Treatment method of dichloromethane in acesulfame potassium production | 安徽金禾实业股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-112107690-B | Preparation method of camptothecine drug nanoparticles | 浙江工业大学 | 2023-05-30 | — | — | CN | claimed |
| CN-116173159-A | Zedoary turmeric oil sulfonate, and preparation method and application thereof | 北京中医药大学东直门医院 | 2023-05-30 | — | — | CN | claimed |
| EP-1680430-A2 | PROCESSES FOR PREPARING DIFFERENT FORMS OF (S)-(+)- CLOPIDOGREL BISULFATE | CADILA HEALTHCARE LTD. (IN) | 2006-07-19 | — | — | EP | claimed |
| WO-2005063708-A2 | PROCESSES FOR PREPARING DIFFERENT FORMS OF (S)-(+)- CLOPIDOGREL BISULFATE | CADILA HEALTHCARE LIMITED (IN) | 2005-07-14 | — | — | WO | claimed |
| US-20050042178-A1 | Microparticles containing the CGRP-antagonist 1-[N2-[3,5-dibrom-N-[[4-(3,4-dihydro-2(1H)-oxoquinazoline-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine, process for preparing and the use thereof as inhalation powder | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-24 | — | — | US | claimed |
| US-6841665-B2 | Method for synthesizing 5β, 6β-epoxides of steroids by a highly β-selective epoxidation of ΔΔ5-unsaturated steroids catalyzed by ketones | THE UNIVERSITY OF HONG KONG (CN) | 2005-01-11 | — | — | US | claimed |
| WO-2003074545-A1 | METHOD FOR SYNTHESIZING 5ß, 6ß-EPOXIDES OF STEROIDS BY A HIGHLY ß-SELECTIVE EPOXIDATION OF Δ5-UNSATURATED STEROIDS CATALYZED BY KETONES | THE UNIVERSITY OF HONG KONG (CN) | 2003-09-12 | — | — | WO | claimed |
| US-20030018188-A1 | Method for synthesizing 5beta, 6beta-epoxides of steroids by a highly beta-selective epoxidation of delta5-unsaturated steroids catalyzed by ketones | UNIVERSITY OF HONG KONG, THE (HK) | 2003-01-23 | — | — | US | claimed |
| CN-1235972-A | Synthesis of 3-EPI vitamin D3 Metabolites and analogs | HOFFMANN LA ROCHE (CH) | 1999-11-24 | — | — | CN | claimed |
| EP-0957098-A1 | Intermediates for the synthesis of 3-epi vitamin D3 metabolites and analogs | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-17 | — | — | EP | claimed |
| US-5438064-A | For suppressing the binding of bradykinins to pain receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-01 | — | — | US | claimed |
| EP-0372157-A1 | Antidiabetic phosphonates | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | claimed |