SCHEMBL3772017

SCHEMBL3772017

C=C[Si](C)(C)C(CC)N(C1CCCCC1)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 5/20 0.35
ADH1C P00326 4/20 0.35
SHBG P04278 1/20 0.32
ADH1B P00325 1/20 0.32
FDPS P14324 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3776316 0.98 ADH1A (0.32) ADH1AADH1C
SCHEMBL3771974 0.78 ADH1C (0.37) ADH1AADH1CADH1BFDPS
SCHEMBL3777424 0.76 ADH1B (0.34) ADH1AADH1CADH1BFDPS
SCHEMBL737493 0.69 SHBG (0.39) ADH1AADH1CSHBGADH1BFDPS
SCHEMBL20988082 0.68 SHBG (0.42) ADH1AADH1CSHBGADH1BFDPS
SCHEMBL3774824 0.68
SCHEMBL3774753 0.66
SCHEMBL737062 0.66 SHBG (0.36) ADH1AADH1CSHBGADH1BFDPS
SCHEMBL2481387 0.66 SHBG (0.41) ADH1AADH1CSHBGADH1BFDPS
SCHEMBL3771552 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436166-B2 Amino-containing vinylsilane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-07 US disclosed
US-20100317852-A1 AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317852-A1 AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD BHMT2, GNMT, VASP ADH1A 4181/4885ADH1C 4556/4885SHBG 3461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.