Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362827 | 0.83 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL351999 | 0.79 | TDP1 (0.34) | CYP2D6DGAT1TET2 | |
| SCHEMBL1812399 | 0.79 | DGAT1 (0.33) | CYP2D6DGAT1TET2ALDH1A1 | |
| SCHEMBL5543011 | 0.77 | DGAT1 (0.32) | DGAT1TET2 | |
| SCHEMBL1520780 | 0.77 | DGAT1 (0.32) | DGAT1TET2 | |
| SCHEMBL12890987 | 0.77 | TDP1 (0.33) | DGAT1TET2 | |
| SCHEMBL11389699 | 0.76 | TRPA1 (0.35) | DGAT1TRPA1AKT1ALDH1A1 | |
| SCHEMBL678671 | 0.76 | CYP2D6 (0.39) | CYP2D6DGAT1TET2ALDH1A1 | |
| SCHEMBL31712055 | 0.76 | DGAT1 (0.35) | DGAT1ALDH1A1 | |
| SCHEMBL395187 | 0.76 | ALDH1A1 (0.36) | DGAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905152-B | Acrylate monomer containing 2-carbonyl bromide and alkynyl, polymer thereof, synthetic method and application | 中国科学院上海有机化学研究所 | 2020-10-30 | — | — | CN | claimed |
| CN-106905152-A | Acrylic ester monomer and its polymer, preparation method and use containing 2 carbonyl bromines and alkynyl | 中国科学院上海有机化学研究所 | 2017-06-30 | — | — | CN | claimed |
| US-8791293-B2 | Fluorine-containing sulfonate, fluorine-containing sulfonate resin, resist composition and pattern formation method | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-07-29 | — | — | US | claimed |
| US-20130065182-A1 | Fluorine-Containing Sulfonate, Fluorine-Containing Sulfonate Resin, Resist Composition and Pattern Formation Method | CENTRAL GLASS COMPANY, LIMITED (JP) | 2013-03-14 | — | — | US | claimed |
| US-12612414-B2 | Nitrile SUMO inhibitors and uses thereof | CIT THERAPEUTICS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20250115574-A1 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | VIB VZW (BE) | 2025-04-10 | — | — | US | disclosed |
| US-20240408093-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. | 2024-12-12 | — | — | US | disclosed |
| WO-2024249950-A1 | FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN | BIOMEA FUSION, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| US-20240360148-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | CIT THERAPEUTICS LLC | 2024-10-31 | — | — | US | disclosed |
| EP-4452936-A2 | INDOLES, INDAZOLES, AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-10-30 | — | — | EP | disclosed |
| EP-4452254-A2 | TETRAHYDROPYRAZOLOPYRIMIDINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-10-30 | — | — | EP | disclosed |
| EP-0391673-A1 | Preparation of glutaric acid derivatives | Pfizer Limited (GB) | 1990-10-10 | — | — | EP | disclosed |
| US-4960792-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0343911-A2 | Cycloalkyl-substituted glutaramide diuretic agents | Pfizer Limited (GB) | 1989-11-29 | — | — | EP | disclosed |
| EP-0274234-A2 | Spiro-subsituted glutaramide diuretic agents | Pfizer Limited (GB) | 1988-07-13 | — | — | EP | disclosed |
| US-4647556-A | Cephalosporin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | disclosed |
| EP-0190900-A2 | Cephalosporin compounds, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-08-13 | — | — | EP | disclosed |
| US-4565818-A | Pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoline derivatives | SANDOZ LTD. (CH) | 1986-01-21 | — | — | US | disclosed |
| EP-0077754-A2 | Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives | SANDOZ AG (CH) | 1983-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552772-B2 | 2-pyrazole anilines and related analogs for inhibiting YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | CYP2D6 3797/4885DGAT1 3137/4885TRPA1 2157/4885 |
| US-20240360148-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | SUMO1, SUMO3, SUMO2 | CYP2D6 3187/4885DGAT1 4005/4885TRPA1 4860/4885 |
| US-12612414-B2 | Nitrile SUMO inhibitors and uses thereof | SUMO1, SUMO3, PSMB6 | CYP2D6 1139/4885DGAT1 3004/4885TRPA1 4877/4885 |
| US-20130065182-A1 | Fluorine-Containing Sulfonate, Fluorine-Containing Sulfonate Resin, Resist Composition and Pattern Formation Method | RARA, PFAS, AFF1 | CYP2D6 2115/4885DGAT1 2685/4885TRPA1 2771/4885 |
| US-20240408093-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | FGFR3, FGFR1, ERBB3 | CYP2D6 4066/4885DGAT1 2423/4885TRPA1 4564/4885 |
| US-20250115574-A1 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | YAP1, TEAD3, TEAD2 | CYP2D6 4269/4885DGAT1 2215/4885TRPA1 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.