Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364449 | 0.98 | ESR1 (0.36) | RAB9ALMNAALOX12SMN1; SMN2ESR1 | |
| SCHEMBL14743627 | 0.94 | RAB9A (0.34) | RAB9ALMNAALOX12SMN1; SMN2ESR1 | |
| SCHEMBL6937164 | 0.81 | HDAC3 (0.40) | RAB9AALOX12SMN1; SMN2NPC1CYP2D6 | |
| SCHEMBL6937935 | 0.80 | MCL1 (0.35) | RAB9ALMNAALOX12SMN1; SMN2MCL1 | |
| SCHEMBL6939059 | 0.78 | MEN1 (0.38) | RAB9ALMNAALOX12SMN1; SMN2MCL1 | |
| SCHEMBL20955841 | 0.74 | MCL1 (0.43) | RAB9ASMN1; SMN2MCL1NPC1POLB | |
| SCHEMBL27714879 | 0.74 | RAB9A (0.39) | RAB9ALMNAALOX12SMN1; SMN2MCL1 | |
| SCHEMBL15364556 | 0.70 | KDM1A (0.41) | LMNAALOX12POLBALDH1A1KDM4E | |
| SCHEMBL15527706 | 0.70 | KDM1A (0.41) | RAB9ALMNAALOX12SMN1; SMN2MCL1 | |
| SCHEMBL30989518 | 0.70 | RAB9A (0.33) | RAB9ALMNAALOX12SMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4585268-A2 | SOLID FORMS OF ISOQUINOLINONE DERIVATIVES, PROCESS OF MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING THE SAME | Twelve Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | claimed |
| CN-119695115-A | Silicon carbon material, preparation method thereof, pole piece, application and lithium ion battery | 上海杉杉新材料有限公司 | 2025-03-25 | — | — | CN | claimed |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | INFINITY PHARMACEUTICALS, INC. (US) | 2024-03-26 | — | — | US | claimed |
| CN-116368134-A | Methods of making ubiquitin JAK inhibitors and related intermediate compounds | 施万生物制药研发IP有限责任公司 | 2023-06-30 | — | — | CN | claimed |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | TWELVE THERAPEUTICS, INC. | 2022-05-05 | — | — | US | claimed |
| CN-112094165-A | Method for preparing biaryl compound by Suzuki coupling reaction | 浙江省化工研究院有限公司 | 2020-12-18 | — | — | CN | claimed |
| US-20170197944-A1 | PROCESS FOR THE PREPARATION OF LEDIPASVIR | Optimus Drugs, LLC (IN) | 2017-07-13 | — | — | US | claimed |
| WO-2017072596-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LEDIPASVIR | OPTIMUS DRUGS (P) LTD (IN) | 2017-05-04 | — | — | WO | claimed |
| US-20260103443-A1 | CHEMICAL COMPOUND | LMS CO LTD (KR) | 2026-04-16 | — | — | US | disclosed |
| US-20260049087-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | TWELVE THERAPEUTICS INC (US) | 2026-02-19 | — | — | US | disclosed |
| EP-4646413-A1 | SOLID FORMS OF A CDK2 INHIBITOR | Blueprint Medicines Corporation (US) | 2025-11-12 | — | — | EP | disclosed |
| US-20250311617-A1 | BORON-CONTAINING RESONANCE ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME | HUAWEI TECH CO LTD (CN) | 2025-10-02 | — | — | US | disclosed |
| EP-4624477-A1 | BORON-CONTAINING RESONANCE-TYPE ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | Huawei Technologies Co., Ltd. (CN) | 2025-10-01 | — | — | EP | disclosed |
| US-12384792-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | TWELVE THERAPEUTICS, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-20120022293-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-2410380-A2 | Electrophotographic photoreceptor | Takasago International Corporation (JP) | 2012-01-25 | — | — | EP | disclosed |
| EP-1167372-B1 | 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-6455720-B1 | AS CATALYSTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |
| US-20020058837-A1 | 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1167372-A1 | 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | Takasago International Corporation (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058837-A1 | 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst | DDT, PDCD11, PLD2 | RAB9A 219/4885LMNA 4620/4885ALOX12 3610/4885 |
| US-20250311617-A1 | BORON-CONTAINING RESONANCE ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME | OR10J3, LEF1, ORC3 | RAB9A 1015/4885LMNA 3120/4885ALOX12 892/4885 |
| US-20260049087-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | PRKCB, PRKCD, PRKCA | RAB9A 1478/4885LMNA 1489/4885ALOX12 3577/4885 |
| US-20120022293-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | SLC1A2, SLC18A2, SLC1A1 | RAB9A 2074/4885LMNA 3928/4885ALOX12 3303/4885 |
| US-12384792-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | PIK3CA, PIK3C2A, PIK3CD | RAB9A 1331/4885LMNA 888/4885ALOX12 3079/4885 |
| US-20170197944-A1 | PROCESS FOR THE PREPARATION OF LEDIPASVIR | SAMHD1, POLI, PNP | RAB9A 1144/4885LMNA 2239/4885ALOX12 3260/4885 |
| US-20260103443-A1 | CHEMICAL COMPOUND | RAD51, CBR1, NOS1 | RAB9A 838/4885LMNA 2654/4885ALOX12 316/4885 |
| US-20220135576-A1 | SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME | PIK3CA, PIK3C2A, PIK3CD | RAB9A 1331/4885LMNA 888/4885ALOX12 3079/4885 |
| US-11939333-B2 | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same | PIK3CA, PIK3C2A, PIK3CD | RAB9A 1331/4885LMNA 888/4885ALOX12 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.