Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 4/20 | 0.40 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.40 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.38 |
| ▸ | P2RY2 known ✓ | P41231 | 3/20 | 0.36 |
| ▸ | P2RY6 known ✓ | Q15077 | 3/20 | 0.36 |
| ▸ | P2RY12 known ✓ | Q9H244 | 3/20 | 0.36 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080398 | 1.00 | FUT8 (0.56) | FUT8ENPP2CARM1PRMT1POLB | |
| SCHEMBL18785035 | 0.87 | FUT8 (0.72) | FUT8ENPP2CARM1PRMT1KMT2A | |
| SCHEMBL11987206 | 0.85 | FUT8 (0.55) | FUT8ENPP2CARM1PRMT1USP2 | |
| SCHEMBL4409511 | 0.84 | FUT8 (0.72) | FUT8ENPP2CARM1PRMT1POLB | |
| SCHEMBL4409516 | 0.84 | FUT8 (0.72) | FUT8ENPP2CARM1PRMT1POLB | |
| SCHEMBL29393807 | 0.84 | FUT8 (0.72) | FUT8ENPP2CARM1PRMT1POLB | |
| SCHEMBL11986735 | 0.84 | FUT8 (0.54) | FUT8ENPP2CARM1PRMT1APEX1 | |
| SCHEMBL18775365 | 0.80 | FUT8 (0.59) | FUT8ENPP2CARM1PRMT1USP2 | |
| SCHEMBL29663889 | 0.80 | FUT8 (0.67) | FUT8ENPP2CARM1PRMT1POLB | |
| SCHEMBL30398956 | 0.79 | PRMT1 (0.53) | FUT8ENPP2CARM1PRMT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4906 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725227-B2 | Devices and methods for examining drug effects on microorganisms | ESSENLIX CORPORATION (US) | 2023-08-15 | — | — | US | claimed |
| EP-2900836-B1 | TWO-PRIMER PCR FOR MICRORNA MULTIPLEX ASSAY | CEPHEID (US) | 2023-05-10 | — | — | EP | claimed |
| US-20220237930-A1 | CELL AGE CLASSIFICATION AND DRUG SCREENING | FOUNTAIN THERAPEUTICS INC (US) | 2022-07-28 | — | — | US | claimed |
| US-20210275693-A1 | MODIFIED WOUND DRESSINGS | CONVATEC TECHNOLOGIES INC. | 2021-09-09 | — | — | US | claimed |
| US-10961571-B2 | Polymerase assay with a FRET substrate | Life Technologies Corporation (US) | 2021-03-30 | — | — | US | claimed |
| US-20200399675-A1 | DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS | ESSENLIX CORPORATION (US) | 2020-12-24 | — | — | US | claimed |
| US-10605805-B2 | Device and system for analyzing a sample, particularly blood, as well as methods of using the same | ESSENLIX CORPORATION (US) | 2020-03-31 | — | — | US | claimed |
| US-20190307904-A1 | MODIFIED WOUND DRESSINGS | CONVATEC TECHNOLOGIES INC (US) | 2019-10-10 | — | — | US | claimed |
| EP-3541960-A2 | METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS | Quest Diagnostics Investments LLC (US) | 2019-09-25 | — | — | EP | claimed |
| US-20190276904-A1 | METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS | QUEST DIAGNOSTICS INVESTMENTS LLC (US) | 2019-09-12 | — | — | US | claimed |
| WO-1998002449-A1 | NUCLEIC ACID AMPLIFICATION OLIGONUCLEOTIDES WITH MOLECULAR ENERGY TRANSFER LABELS AND METHODS BASED THEREON | ONCOR, INC. (US) | 1998-01-22 | — | — | WO | claimed |
| US-5565322-A | PHOTOELECTRIC DEVICES; DETECTORS; MEDICAL DIAGNOSIS | NANOGEN, INC. (US) | 1996-10-15 | — | — | US | claimed |
| US-5532129-A | Self-organizing molecular photonic structures based on chromophore- and fluorophore-containing polynucleotides and methods of their use | ENTERPRISE PARTNERS II, L.P. (US) | 1996-07-02 | — | — | US | claimed |
| US-5523214-A | MIXING METHYLENE BLUE, RESAZURIN AND REDOX STABILIZERS INTO SAMPLES FOR COLOR CHANGES WHEN BACTERIA ARE PRESENT, FOR TESTING THEIR SENSITIVITY TO ANTIBIOTICS | BIOTEST AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | claimed |
| EP-0620822-A4 | HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM. | NANOTRONICS INC (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0625581-A1 | Method for the optical detection of microorganisms, their identification and antibiotic sensitivity testing using a redox-indicator system | BIOTEST AG (DE) | 1994-11-23 | — | — | EP | claimed |
| EP-0620822-A1 | HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM | NANOTRONICS, INC. (US) | 1994-10-26 | — | — | EP | claimed |
| WO-1993009128-A1 | HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM | NANOTRONICS, INC. (US) | 1993-05-13 | — | — | WO | claimed |
| EP-0223501-A2 | Waterfast ink jet compositions and process | XEROX CORPORATION (US) | 1987-05-27 | — | — | EP | claimed |
| US-4664708-A | POLYMERIC DYE | XEROX CORPORATION (US) | 1987-05-12 | — | — | US | claimed |