Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088177 | 1.00 | ESR2 (0.42) | ESR2BRD4MMP3MMP8 | |
| SCHEMBL18995729 | 1.00 | ESR2 (0.42) | ESR2BRD4MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL29210817 | 0.97 | ESR2 (0.41) | ESR2 | |
| Hydrochloric Acid SCHEMBL31177800 | 0.97 | ESR2 (0.41) | ESR2 | |
| SCHEMBL24197652 | 0.85 | ESR2 (0.50) | ESR2BRD4MMP3MMP8 | |
| SCHEMBL240852 | 0.85 | ESR2 (0.50) | ESR2BRD4MMP3MMP8 | |
| SCHEMBL5733 | 0.85 | — | — | |
| SCHEMBL8610940 | 0.84 | — | — | |
| SCHEMBL14639005 | 0.84 | LMNA (0.34) | ESR2 | |
| SCHEMBL22844243 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122542-A1 | PROCESS TO PRODUCE (1R,4R)-4-SUBSTITUTED CYCLOHEXANE-1-AMINES | RICHTER GEDEON NYRT (HU) | 2025-04-17 | — | — | US | claimed |
| EP-4402276-A1 | PROCESS TO PRODUCE (1 R, 4 R)-4-SUBSTITUTED CYCLOHEXANE-1-AMINES | Richter Gedeon Nyrt. (HU) | 2024-07-24 | — | — | EP | claimed |
| CN-118043471-A | Process for the production of (1 r,4 r) -4-substituted cyclohexane-1-amines | 吉瑞工厂 | 2024-05-14 | — | — | CN | claimed |
| WO-2023042081-A1 | PROCESS TO PRODUCE (1r,4r)-4-SUBSTITUTED CYCLOHEXANE-1-AMINES | RICHTER GEDEON NYRT. (HU) | 2023-03-23 | — | — | WO | claimed |
| CN-213131969-U | Rotary evaporator for producing trans-4-aminocyclohexane ethanol | 泰州精英化成医药科技有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-110240548-A | A kind of preparation method of Cariliprazine intermediate | 上虞京新药业有限公司 | 2019-09-17 | — | — | CN | claimed |
| US-9718795-B2 | 1,4-cyclohexylamine derivatives and processes for the preparation thereof | CHEMO RESEARCH, S.L. (ES) | 2017-08-01 | — | — | US | claimed |
| EP-3057942-B1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CHEMO RES S L (ES) | 2017-06-14 | — | — | EP | claimed |
| US-20160257661-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CHEMO RESEARCH, S.L. (ES) | 2016-09-08 | — | — | US | claimed |
| EP-3057942-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Chemo Research, S.L. (ES) | 2016-08-24 | — | — | EP | claimed |
| EP-3056198-A2 | USE OF COMPOUNDS FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO CHONDROCYTES | MSP Co., Ltd (KR) | 2016-08-17 | — | — | EP | claimed |
| EP-2617415-B1 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) | 2016-04-20 | — | — | EP | claimed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | claimed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | claimed |
| WO-2015056164-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CHEMO RESEARCH, S.L. (ES) | 2015-04-23 | — | — | WO | claimed |
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2013-09-12 | — | — | US | claimed |
| EP-2617415-A2 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | Industry-Academic Cooperation Foundation, Yonsei University (KR) | 2013-07-24 | — | — | EP | claimed |
| JP-2007514704-A | — | — | 2007-06-07 | — | — | JP | claimed |
| EP-1737857-A1 | PYRAZOLO[3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-01-03 | — | — | EP | claimed |
| WO-2005058892-A1 | PYRAZOLO [3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | COL2A1, MYADM, COL1A1 | ESR2 1727/4885BRD4 1627/4885MMP3 310/4885 |
| US-20160257661-A1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CYP4Z1, PNMT, HTR5A | ESR2 4502/4885BRD4 417/4885MMP3 3624/4885 |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | COL2A1, MYADM, COL1A1 | ESR2 1980/4885BRD4 2051/4885MMP3 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.