SCHEMBL3780735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3784534	0.91	MCHR1 (0.49)	CYP1A2CYP2C9CYP2C19MCHR1L3MBTL1
	SCHEMBL7921354	0.89	CYP1A2 (0.70)	CYP1A2CYP2C9CYP2C19MCHR1MAPT
	SCHEMBL3791890	0.83	ALDH1A1 (0.53)	L3MBTL1MAPTGLATLR8MEN1
	SCHEMBL12968474	0.81	CYP1A2 (0.57)	CYP1A2CYP2C9CYP2C19MCHR1L3MBTL1
	SCHEMBL9621758	0.81	CYP1A2 (0.61)	CYP1A2CYP2C9CYP2C19MCHR1MAPT
	SCHEMBL30167630	0.81	L3MBTL1 (0.66)	CYP1A2CYP2C9CYP2C19L3MBTL1MAPT
	SCHEMBL3794754	0.81	L3MBTL1 (0.66)	CYP1A2CYP2C9CYP2C19L3MBTL1MAPT
	SCHEMBL7927085	0.81	MCHR1 (0.61)	CYP1A2CYP2C9CYP2C19MCHR1MAPT
	SCHEMBL7933101	0.81	MCHR1 (0.61)	CYP1A2CYP2C9CYP2C19MCHR1MAPT
	SCHEMBL3787026	0.80	L3MBTL1 (0.57)	CYP1A2CYP2C9CYP2C19MCHR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.