Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786555 | 0.86 | TDP1 (0.50) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL6943718 | 0.85 | PLAAT5 (0.48) | CA12CA7CA14PLAAT5PLAAT4 | |
| SCHEMBL7060693 | 0.84 | ALDH1A1 (0.52) | CA12CA1CA7CA14PLAAT5 | |
| SCHEMBL17844769 | 0.81 | ADRB2 (0.49) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL30678936 | 0.80 | ALOX5 (0.48) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL1948655 | 0.77 | CA12 (0.50) | CA12CA1CA7CA14CTSK | |
| SCHEMBL3786487 | 0.77 | HDAC2 (0.53) | CA12CA1CA7CA14CTSK | |
| SCHEMBL6345188 | 0.76 | CTSK (0.51) | CA12CA1CA7CA14CTSK | |
| SCHEMBL27871609 | 0.75 | ALDH1A1 (0.46) | CA12CA1CA7CA14CTSK | |
| SCHEMBL15884467 | 0.75 | ALDH1A1 (0.59) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827943-B1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORP (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6150567-A | REACTING CARBONYL COMPOUND WITH ORGANOALUMINUM COMPOUND TO FORM AN ALCOHOL COMPOUND | KANEKA CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0827943-A1 | PROCESSES FOR THE REDUCTION OF CARBONYL COMPOUNDS | KANEKA CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |