Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27765603 | 0.98 | NR3C1 (0.51) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL28322905 | 0.98 | NR3C1 (0.51) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL30136554 | 0.81 | AR (0.53) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL1018276 | 0.81 | AR (0.53) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL30136569 | 0.81 | NR3C1 (0.53) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL593678 | 0.81 | NR3C1 (0.62) | NR3C1PGRNR3C2ARKEAP1 | |
| Hydrochloric Acid SCHEMBL26614912 | 0.79 | AR (0.51) | NR3C1PGRNR3C2ARKEAP1 | |
| Sulfuric Acid SCHEMBL23540701 | 0.77 | KEAP1 (0.50) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL3792302 | 0.77 | NR3C1 (0.53) | NR3C1PGRNR3C2ARKEAP1 | |
| SCHEMBL4485961 | 0.77 | NR3C1 (0.57) | NR3C1PGRNR3C2ARKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270748-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2024-08-15 | — | — | US | claimed |
| CN-107207433-A | New organic compound, the near infrared fluorescent contrast agent containing the compound and the method for preparing nano particle contrast agent | 车医科学大学校产学协力团 | 2017-09-26 | — | — | CN | claimed |
| CN-107207433-A | New organic compound, the near infrared fluorescent contrast agent containing the compound and the method for preparing nano particle contrast agent | 车医科学大学校产学协力团 | 2017-09-26 | — | — | CN | disclosed |
| CN-101001837-B | Indole derivatives comprising an acetylene group as PPAR activators | HOFFMANN LA ROCHE | 2012-11-07 | — | — | CN | disclosed |
| US-7645400-B2 | Composition containing carbon nanotubes having a coating | MITSUBISHI RAYON CO., LTD. (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20090321688-A1 | Carbon Nanotube Composition, Composite Having a Coated Film Composed of the Same, and Their Production Methods | MITSUBISHI RAYON CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7585981-B2 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI RAYON CO., LTD. (JP) | 2009-09-08 | — | — | US | disclosed |
| CN-101466728-A | HCV inhibitors comprising beta amino acids and their uses | NOVARTIS AG (CH) | 2009-06-24 | — | — | CN | disclosed |
| CN-101421292-A | HCV inhibitors | NOVARTIS AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| EP-2007787-A2 | HCV INHIBITORS COMPRISING BETA AMINO ACIDS AND THEIR USES | Novartis AG (CH) | 2008-12-31 | — | — | EP | disclosed |
| EP-2007788-A2 | HCV INHIBITORS | Novartis AG (CH) | 2008-12-31 | — | — | EP | disclosed |
| US-20070265281-A1 | Organic Compounds and Their Uses | COTTENS SYLVAIN | 2007-11-15 | — | — | US | disclosed |
| WO-2007121125-A2 | HCV INHIBITORS | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121124-A2 | HCV INHIBITORS COMPRISING BETA AMINO ACIDS AND THEIR USES | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |
| CN-101001837-A | Indole derivatives comprising an acetylene group as PPAR activators | HOFFMANN LA ROCHE (CH) | 2007-07-18 | — | — | CN | disclosed |
| US-7115751-B2 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI RAYON CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20060211793-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI RAYONE CO., LTD. (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20060052509-A1 | Composition containing carbon nanotubes having coating thereof and process for producing them | MITSUBISHI RAYON CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |
| US-20040019097-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| EP-1327632-A1 | METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF | Mitsubishi Rayon Co., Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270748-A1 | TRICYCLIC HETEROCYCLES | YAP1, TERF2IP, TEAD1 | NR3C1 2584/4885PGR 2675/4885NR3C2 2851/4885 |
| US-20060211793-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | IDO1, IDO2, INMT | NR3C1 2378/4885PGR 2905/4885NR3C2 1851/4885 |
| US-20040019097-A1 | Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof | IDO1, IDO2, INMT | NR3C1 2535/4885PGR 2769/4885NR3C2 2023/4885 |
| US-20070265281-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | NR3C1 788/4885PGR 1679/4885NR3C2 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.