Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379140 | 0.81 | TRPM8 (0.50) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL379142 | 0.81 | TRPM8 (0.50) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL7715071 | 0.75 | TSHR (0.52) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL12411238 | 0.70 | LMNA (0.48) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL10973737 | 0.69 | MAPT (0.47) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL30495367 | 0.69 | MAPT (0.47) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL11203024 | 0.69 | MAPT (0.47) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL21808158 | 0.67 | MAPT (0.49) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL21808157 | 0.67 | MAPT (0.49) | NISCHTRPM8ALDH1A1TSHRAKR1C3 | |
| SCHEMBL21340590 | 0.67 | TSHR (0.44) | NISCHTRPM8ALDH1A1TSHRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782921-B1 | ORGANIC TUNGSTEN COMPLEXES | VANDERBILT CHEMICALS LLC (US) | 2018-05-02 | — | — | EP | disclosed |
| US-8669386-B2 | Organic tungsten complexes | VANDEBILT CHEMICALS, LLC (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120165563-A1 | ORGANIC TUNGSTEN COMPLEXES | R.T. VANDERBILT COMPANY, INC. | 2012-06-28 | — | — | US | disclosed |
| EP-2137199-A1 | ORGANIC TUNGSTEN COMPLEXES | R.T. Vanderbilt Company, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008116099-A1 | ORGANIC TUNGSTEN COMPLEXES | R.T. VANDERBILT COMPANY, INC. (US) | 2008-09-25 | — | — | WO | disclosed |
| US-20080234154-A1 | ORGANIC TUNGSTEN COMPLEXES | R.T. VANDERBILT COMPANY, INC. (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234154-A1 | ORGANIC TUNGSTEN COMPLEXES | DGAT2, DGAT1, DGKI | NISCH 1670/4885TRPM8 3153/4885ALDH1A1 2307/4885 |
| US-20120165563-A1 | ORGANIC TUNGSTEN COMPLEXES | ADH5, ELOVL5, ALOX5 | NISCH 1479/4885TRPM8 1617/4885ALDH1A1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.