Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610618 | 0.81 | ACACB (0.41) | RAB9ANPC1 | |
| SCHEMBL610619 | 0.71 | MAOA (0.56) | ACHE | |
| SCHEMBL1716115 | 0.70 | SIGMAR1 (0.55) | SMN1; SMN2THRB | |
| SCHEMBL610818 | 0.69 | PYCR1 (0.60) | ACHESMN1; SMN2HDAC6 | |
| Hydrochloric Acid SCHEMBL10889430 | 0.69 | SIGMAR1 (0.53) | SMN1; SMN2 | |
| SCHEMBL8893720 | 0.63 | LIPE (0.56) | SMN1; SMN2 | |
| SCHEMBL20766522 | 0.62 | NPC1 (1.00) | RAB9ANPC1FAAH | |
| SCHEMBL20214592 | 0.62 | PTGS2 (0.51) | RAB9ANPC1 | |
| SCHEMBL21410253 | 0.62 | PYCR1 (0.51) | RAB9ANPC1ACHEANPEPTHRA | |
| SCHEMBL27792799 | 0.62 | SLC6A4 (0.53) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086860-A2 | NEUROPROTECTIVE MULTIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-08-05 | — | — | WO | disclosed |