SCHEMBL379780

SCHEMBL379780

CCC1(CC)c2[c]cccc2-c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.36
APEX1 P27695 1/20 0.36
CYP2D6 P10635 1/20 0.34
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
PDK2 Q15119 1/20 0.30
KCNQ2 O43526 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2409247 0.87 ELANE (0.31) ELANE
SCHEMBL10010105 0.86 PGR (0.39) PGRAPEX1CYP2D6PDK2
SCHEMBL2410922 0.84 CYP2D6 (0.30) PGRCYP2D6
SCHEMBL10009392 0.83 APEX1 (0.36) PGRAPEX1CYP2D6CYP2C19PDK2
SCHEMBL2407449 0.83
SCHEMBL2409026 0.83
SCHEMBL4879225 0.81 MMP2 (0.38) PGRAPEX1CYP2C19KMT2APDK2
SCHEMBL447132 0.81 MMP2 (0.38) PGRAPEX1CYP2C19KMT2APDK2
SCHEMBL2408539 0.81 PGR (0.35) PGRAPEX1CYP2D6CYP1A2CYP2C19
SCHEMBL2411559 0.78 APEX1 (0.37) PGRAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557956-A Large condensed ring organic compound, application thereof and organic electroluminescent device comprising large condensed ring organic compound 北京鼎材科技有限公司 2023-01-03 CN claimed
CN-115477587-A Organic compound, application thereof and organic electroluminescent device comprising organic compound 北京鼎材科技有限公司 2022-12-16 CN claimed
CN-115340464-A Organic compound, application thereof and organic electroluminescent device comprising organic compound 北京鼎材科技有限公司 2022-11-15 CN claimed
CN-115340515-A Organic compound, application thereof and organic electroluminescent device comprising organic compound 北京鼎材科技有限公司 2022-11-15 CN claimed
CN-113563348-A Compound and application thereof in organic electroluminescent device 北京云基科技有限公司 2021-10-29 CN claimed
CN-113563349-A Spiro pyrrolocarbazole compound, application thereof and organic electroluminescent device using same 北京云基科技有限公司 2021-10-29 CN claimed
WO-2024103552-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS 昆山国显光电有限公司 2024-05-23 WO disclosed
WO-2024103553-A1 ORGANIC LIGHT-EMITTING DIODE AND DISPLAY APPARATUS 昆山国显光电有限公司 2024-05-23 WO disclosed
WO-2024088237-A1 LUMINESCENT MATERIAL, USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME 清华大学 2024-05-02 WO disclosed
WO-2024088239-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 清华大学 2024-05-02 WO disclosed
CN-115894457-A Organic compound and application thereof 北京鼎材科技有限公司 2023-04-04 CN disclosed
CN-115811891-A Organic electroluminescent device and display device 昆山国显光电有限公司 2023-03-17 CN disclosed
CN-115745976-A Luminescent material, application thereof and organic electroluminescent device comprising luminescent material 清华大学 2023-03-07 CN disclosed
US-20110272683-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-11-10 US disclosed
US-20110240974-A1 NOVEL BENZO[b]CHRYSENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-10-06 US disclosed
WO-2010107097-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-09-23 WO disclosed
WO-2010107037-A1 NOVEL CHRYSENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-09-23 WO disclosed
EP-2045231-B1 Binaphthyl compound and organic light emitting element using the same CANON KK (JP) 2010-07-21 EP disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
EP-2045231-A1 Binaphthyl compound and organic light emitting element using the same Canon Kabushiki Kaisha (JP) 2009-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME ALPL, MT-ND4L, LAGE3 PGR 2596/4885APEX1 2088/4885CYP2D6 553/4885
US-20110240974-A1 NOVEL BENZO[b]CHRYSENE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME AHR, NR0B2, NR0B1 PGR 350/4885APEX1 2965/4885CYP2D6 591/4885
US-20110272683-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND PPOX, CRY1, OXER1 PGR 2247/4885APEX1 1004/4885CYP2D6 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.