Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797300 | 0.74 | HPGD (0.38) | DRD1DRD4DRD3HPGDMEN1 | |
| SCHEMBL5653503 | 0.71 | HPGD (0.36) | DRD4HTTHPGDMEN1KMT2A | |
| SCHEMBL10530927 | 0.69 | KMT2A (0.38) | DRD3MAPTHTTHPGDALDH1A1 | |
| SCHEMBL12353478 | 0.66 | ALDH1A1 (0.34) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL10534696 | 0.66 | SHMT2 (0.36) | DRD3MAPTATMHTTHPGD | |
| SCHEMBL3801753 | 0.64 | MEN1 (0.40) | SIGMAR1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL29221145 | 0.64 | HPGD (0.42) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL11798652 | 0.63 | HPGD (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL3867146 | 0.59 | OPRM1 (0.55) | DRD2SIGMAR1DRD4HRH3 | |
| SCHEMBL17966099 | 0.59 | RECQL (0.38) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829044-B2 | Phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-11-09 | — | — | US | disclosed |
| US-7829044-B2 | Phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-1496063-B1 | EXTRACTION PROCESS FOR RARE EARTH METAL IONS USING A PHOSPHONAMIDE COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-08-19 | — | — | EP | disclosed |
| US-20050107599-A1 | Novel phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-05-19 | — | — | US | disclosed |
| EP-1496063-A1 | NOVEL PHOSPHONAMIDES, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Japan Science and Technology Agency (JP) | 2005-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107599-A1 | Novel phosphonamides, process for producing the same, and use thereof | PHYKPL, CDKL1, MASTL | DRD2 4047/4885SIGMAR1 4079/4885DRD1 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.