Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20759673 | 0.77 | MEN1 (0.38) | L3MBTL1ATMTDP1NPSR1ALDH1A1 | |
| SCHEMBL2866274 | 0.74 | NPSR1 (0.41) | L3MBTL1NPSR1ALDH1A1GLATSHR | |
| SCHEMBL483415 | 0.74 | NPSR1 (0.44) | L3MBTL1ATMTDP1NPSR1ALDH1A1 | |
| SCHEMBL25166823 | 0.74 | L3MBTL1 (0.39) | L3MBTL1ATMTDP1NPSR1ALDH1A1 | |
| SCHEMBL2394240 | 0.72 | NPSR1 (0.43) | L3MBTL1ATMTDP1NPSR1ALDH1A1 | |
| SCHEMBL11011944 | 0.71 | NPSR1 (0.41) | L3MBTL1ATMTDP1NPSR1ALDH1A1 | |
| SCHEMBL15611386 | 0.69 | NPSR1 (0.40) | NPSR1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL4560019 | 0.69 | L3MBTL1 (0.46) | L3MBTL1TDP1NPSR1ALDH1A1HPGD | |
| SCHEMBL17923422 | 0.67 | ALDH1A1 (0.40) | NPSR1ALDH1A1GLATSHRRAB9A | |
| SCHEMBL3799519 | 0.67 | NPC1 (0.32) | ALDH1A1MAPTTSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139888-A2 | IMIDAZOÝ1,2-A¨PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008121687-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-09 | — | — | WO | disclosed |