Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL28859237 | 0.91 | PAX8 (0.34) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL731186 | 0.80 | ITGA4 (0.38) | MEN1KMT2ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL28506622 | 0.80 | NPSR1 (0.39) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL504005 | 0.77 | L3MBTL1 (0.55) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL8736767 | 0.77 | MEN1 (0.43) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL3799516 | 0.77 | L3MBTL1 (0.36) | MEN1KMT2ANPSR1RAB9ACYP2C9 | |
| SCHEMBL23113822 | 0.76 | MEN1 (0.45) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29903353 | 0.76 | CHRM4 (0.36) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL7200107 | 0.75 | RAB9A (0.57) | MEN1KMT2ANPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL7363893 | 0.75 | KDM4E (0.45) | MEN1KMT2ANPSR1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043788-A | Trifluoromethyl oxazole-2-ketone compound and preparation method and application thereof | 南京工业大学 | 2022-09-13 | — | — | CN | disclosed |
| US-11174226-B2 | Azetidinimines as carbapenemases inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-11-16 | — | — | US | disclosed |
| US-20190055194-A1 | Azetidinimines as Carbapenemases Inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174226-B2 | Azetidinimines as carbapenemases inhibitors | OXA1L, QDPR, PADI1 | MEN1 944/4885KMT2A 1596/4885NPSR1 3223/4885 |
| US-20190055194-A1 | Azetidinimines as Carbapenemases Inhibitors | OXA1L, QDPR, PADI1 | MEN1 944/4885KMT2A 1596/4885NPSR1 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.