Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.76 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.62 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | FABP2 | P12104 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28343515 | 0.97 | PTGS2 (0.72) | PTGS2MT-CO2METTL3MEN1MAPK1 | |
| SCHEMBL4434232 | 0.82 | METTL3 (0.76) | PTGS2MT-CO2METTL3MEN1MAPK1 | |
| SCHEMBL29481381 | 0.82 | METTL3 (0.76) | PTGS2MT-CO2METTL3MEN1MAPK1 | |
| SCHEMBL12608889 | 0.81 | PTGS2 (0.74) | PTGS2MT-CO2METTL3MEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL2582024 | 0.81 | METTL3 (0.74) | PTGS2MT-CO2METTL3MEN1MAPK1 | |
| SCHEMBL9268418 | 0.80 | PTGS2 (0.77) | PTGS2MT-CO2METTL3MEN1MAPK1 | |
| Acetic Acid SCHEMBL16049910 | 0.79 | METTL3 (0.71) | PTGS2METTL3MEN1MAPK1KMT2A | |
| SCHEMBL9734401 | 0.79 | PTGS2 (0.75) | PTGS2MT-CO2METTL3MEN1MAPK1 | |
| Meclofenamic Acid SCHEMBL28346421 | 0.79 | PTGS2 (0.67) | PTGS2METTL3MEN1MAPK1KMT2A | |
| SCHEMBL3805715 | 0.78 | MT-CO2 (0.59) | PTGS2MT-CO2MEN1KMT2AAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | PTGS2 7/4885MT-CO2 4662/4885METTL3 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.