SCHEMBL3818448

SCHEMBL3818448

O=C1C=CC(=O)N1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.46
HCAR1 Q9BXC0 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
USP2 O75604 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
FPR1 P21462 1/20 0.34
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16369105 0.79 PKM (0.39) EPHX2ALDH1A1
SCHEMBL4147819 0.78 EPHX2 (0.32) EPHX2
SCHEMBL4848551 0.71 ADORA3 (0.31)
SCHEMBL3826438 0.71 EPHX2 (0.44) EPHX2HCAR1SMN1; SMN2MAPK1HSD17B10
SCHEMBL29625381 0.70 ALDH1A1 (0.50) EPHX2SMN1; SMN2MAPK1HSD17B10USP2
SCHEMBL24120009 0.68 EPHX2 (0.50) EPHX2MAPTKDM4EMEN1ALDH1A1
SCHEMBL16369112 0.66 EPHX2 (0.40) EPHX2HCAR1FPR1KDM4EMEN1
SCHEMBL16369104 0.66 EPHX2 (0.43) EPHX2
SCHEMBL7803028 0.65 CES1 (0.43) EPHX2MAPTALDH1A1
SCHEMBL7358160 0.64 ALDH1A1 (0.50) EPHX2HCAR1SMN1; SMN2USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
CN-122054878-A Method for manufacturing light-emitting device, negative-type radiation-sensitive composition, cured film, and organic EL device JSR株式会社 2026-05-15 CN disclosed
CN-120077771-A Curable composition for organic EL element, cured product for organic EL element, method for producing cured product for organic EL element, and polymer JSR株式会社 2025-05-30 CN disclosed
WO-2024248064-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME, COPPER PASTE, LIQUID COMPOSITION, METHOD FOR PRODUCING SEMICONDUCTOR DEVICE, AND METHOD FOR PRODUCING COPPER PILLAR FOR SEMICONDUCTOR CONNECTION 株式会社ダイセル 2024-12-05 WO disclosed
WO-2024248066-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME, COPPER PASTE, LIQUID COMPOSITION, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING COPPER PILLAR FOR SEMICONDUCTOR CONNECTION 株式会社ダイセル 2024-12-05 WO disclosed
WO-2024248065-A1 POLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME, COPPER PASTE, LIQUID COMPOSITION, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING COPPER PILLAR FOR SEMICONDUCTOR CONNECTION 株式会社ダイセル 2024-12-05 WO disclosed
CN-119065201-A Radiation-sensitive composition, cured film, method for producing same, semiconductor element, and display element JSR株式会社 2024-12-03 CN disclosed
WO-2024242171-A1 RADIATION-SENSITIVE COMPOSITION FOR FORMING GATE INSULATING FILM, PATTERN, METHOD FOR PRODUCING PATTERN, CURED FILM FOR GATE INSULATING FILM, SEMICONDUCTOR ELEMENT, ORGANIC ELECTROCHEMICAL TRANSISTOR, ORGANIC EL DISPLAY DEVICE, LIQUID CRYSTAL DISPLAY DEVICE, MICRO-LED DISPLAY DEVICE, QUANTUM DOT LIGHT-EMITTING DISPLAY DEVICE, WEARABLE DEVICE, ELECTRONIC SKIN DEVICE, BIOLOGICAL SENSOR, AND NEUROMORPHIC DEVICE JSR株式会社 2024-11-28 WO disclosed
CN-118818897-A Radiation-sensitive composition, cured film, method for producing same, semiconductor element, and display element JSR株式会社 2024-10-22 CN disclosed
CN-118795734-A Radiation-sensitive composition, cured film, method for producing cured film, liquid crystal display device, and organic EL display device JSR株式会社 2024-10-18 CN disclosed
EP-2094649-A2 MATERIALS AND METHODS FOR CO-CRYSTAL CONTROLLED SOLID-STATE SYNTHESIS OF IMIDES AND IMINES University of South Florida (US) 2009-09-02 EP disclosed
US-20090124776-A1 Cycloaliphatic epoxy (meth)acrylates, preparation processes thereof, and copolymers DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-05-14 US disclosed
EP-2048196-A1 CURABLE RESIN COMPOSITION AND METHOD FOR FORMING CURED COATING FILM Daicel Chemical Industries, Ltd. (JP) 2009-04-15 EP disclosed
WO-2008073613-A2 MATERIALS AND METHODS FOR CO-CRYSTAL CONTROLLED SOLID-STATE SYNTHESIS OF IMIDES AND IMINES UNIVERSITY OF SOUTH FLORIDA (US) 2008-06-19 WO disclosed
US-20080146772-A1 MATERIALS AND METHODS FOR CO-CRYSTAL CONTROLLED SOLID-STATE SYNTHESIS OF IMIDES AND IMINES UNIVERSITY OF SOUTH FLORIDA (US) 2008-06-19 US disclosed
US-7365231-B2 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-04-29 US disclosed
EP-1818327-A1 ALICYCLIC EPOXY (METH)ACRYLATES, PROCESS FOR PRODUCTION THEREOF, AND COPOLYMERS Daicel Chemical Industries, Ltd. (JP) 2007-08-15 EP disclosed
US-20060241187-A1 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2006-10-26 US disclosed
US-20010034333-A1 Cyclodextrin polymer compositions for use as drug carriers KOSAK KENNETH M (US) 2001-10-25 US disclosed
US-5502135-A NONLINEAR OPTICAL BASF AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010034333-A1 Cyclodextrin polymer compositions for use as drug carriers ABCB1, ABCG2, CTTN EPHX2 910/4885HCAR1 1798/4885SMN1; SMN2 3278/4885
US-20060241187-A1 Compound with antitumor activity and preparation method therefor WEE1, WEE2, CYP51A1 EPHX2 963/4885HCAR1 1534/4885SMN1; SMN2 4670/4885
US-20090124776-A1 Cycloaliphatic epoxy (meth)acrylates, preparation processes thereof, and copolymers MEP1B, MEP1A, ACMSD EPHX2 72/4885HCAR1 1036/4885SMN1; SMN2 1461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.