Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.79 |
| ▸ | MGAM | O43451 | 1/20 | 0.79 |
| ▸ | SI | P14410 | 1/20 | 0.79 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL6157602 | 0.90 | GAA (0.64) | GAAMGAMSIMGAM2ALOX15 | |
| Malonic Acid Diethyl Ester SCHEMBL27943809 | 0.89 | GAA (0.88) | GAAMGAMSIMGAM2ALOX15 | |
| Malonic Acid Diethyl Ester SCHEMBL1330550 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALOX15 | |
| Malonic Acid Diethyl Ester SCHEMBL8636 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALOX15 | |
| Malonic Acid Diethyl Ester SCHEMBL1331824 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALOX15 | |
| Malonic Acid Diethyl Ester SCHEMBL1331187 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALOX15 | |
| Malonic Acid Diethyl Ester SCHEMBL1864301 | 0.89 | GAA (1.00) | GAAMGAMSIMGAM2ALOX15 | |
| Acetamide SCHEMBL27868109 | 0.88 | GAA (0.61) | GAAMGAMSIMGAM2ALOX15 | |
| SCHEMBL27996403 | 0.87 | — | — | |
| Malonic Acid Diethyl Ester SCHEMBL29008218 | 0.86 | GAA (0.83) | GAAMGAMSIMGAM2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101444496-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP (US) | 2009-06-03 | — | — | CN | claimed |
| CN-1608055-A | Compounds for the treatment of metabolic disorders | WELLSTAT THERAPEUTICS CORP (US) | 2005-04-20 | — | — | CN | claimed |
| CN-111433577-A | Temperature detection label and article management device using same | 株式会社日立制作所 | 2020-07-17 | — | — | CN | disclosed |
| CN-111057001-A | Preparation method of quinolone malonate compound | 巨化集团公司制药厂 | 2020-04-24 | — | — | CN | disclosed |
| CN-110114647-A | Temperature detection material, temperature detection ink using same, temperature indicator, method for manufacturing temperature detection material, and article management system | 株式会社日立产机系统 | 2019-08-09 | — | — | CN | disclosed |
| WO-2019142480-A1 | TEMPERATURE DETECTION INK, TEMPERATURE DETECTION INK INITIALIZATION METHOD, TEMPERATURE INDICATOR, AND ARTICLE MANAGEMENT SYSTEM | 株式会社日立製作所 | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142485-A1 | TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME | 株式会社日立製作所 | 2019-07-25 | — | — | WO | disclosed |
| CN-101346346-B | Amine compound and use thereof for medical purposes | MITSUBISH TANABE PHARMA CORP | 2012-08-22 | — | — | CN | disclosed |
| CN-100537541-C | Improved process for preparing rebamipide | OTSUKA PHARMA CO LTD (JP) | 2009-09-09 | — | — | CN | disclosed |
| EP-2096111-A1 | PYRAZOLES AND USE THEREOF AS DRUGS | Japan Tobacco Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO, INC. (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-1177861-C | Macrocyclic Peptides Effective Against Hepatitis C Virus | ���ָ����Ӣ��ķ���ô�����˾ | 2004-12-01 | — | — | CN | disclosed |
| EP-0989113-B1 | A PROCESS FOR PREPARING 2-AMINOMALONIC ACID DERIVATIVES | TAITO CO (JP) | 2004-11-10 | — | — | EP | disclosed |
| CN-1480450-A | 2-aminopropane-1,3-glycol compound, its use as medicine and its synthetic intermediate | ������ҩ��ʽ���� | 2004-03-10 | — | — | CN | disclosed |
| CN-1137086-C | 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof | ������ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| CN-1346365-A | Macrocyclic Peptides Effective Against Hepatitis C Virus | BOEHRINGER INGELHEIM CA LTD (CA) | 2002-04-24 | — | — | CN | disclosed |
| US-6284915-B2 | Process for preparing 2-amino malonic acid derivatives and 2-amino-1,3-propanediol derivatives, and intermediates for preparing the same | TAITO CO., LTD (JP) | 2001-09-04 | — | — | US | disclosed |
| US-20010008945-A1 | PROCESS FOR PREPARING 2-AMINO MALONIC ACID DERIVATIVES AND 2-AMINO-1,3 - PROPANEDIOL DERIVATIVES, AND INTERMEDIATES FOR PREPARING THE SAME | MITSUBISHI PHARMA CORPORATION (JP) | 2001-07-19 | — | — | US | disclosed |
| CN-1259117-A | 2-aminopropane-1, 3-diol compound, use thereof as medicine and synthetic intermediate thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2000-07-05 | — | — | CN | disclosed |
| EP-0989113-A1 | PROCESSES FOR PRODUCING 2-AMINOMALONIC ACID DERIVATIVES AND 2-AMINO-1,3-PROPANEDIOL DERIVATIVES, AND INTERMEDIATES FOR PRODUCING THE DERIVATIVES | TAITO CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008945-A1 | PROCESS FOR PREPARING 2-AMINO MALONIC ACID DERIVATIVES AND 2-AMINO-1,3 - PROPANEDIOL DERIVATIVES, AND INTERMEDIATES FOR PREPARING THE SAME | BCAT2, BCAT1, BCKDK | GAA 1782/4885MGAM 346/4885SI 894/4885 |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | PYGL, GYS2, G6PC1 | GAA 81/4885MGAM 48/4885SI 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.