SCHEMBL382722

SCHEMBL382722

CC(C)(C)OC(=O)NCCN=C=S

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
NPSR1 Q6W5P4 1/20 0.43
KEAP1 Q14145 5/20 0.43
NFE2L2 Q16236 5/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
GFER P55789 2/20 0.43
ALDH1A1 P00352 1/20 0.43
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
EPHX1 P07099 1/20 0.41
HTT P42858 1/20 0.38
STK17B O94768 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4565127 0.91 TDP1 (0.44) TDP1MEN1GAAKMT2ACA12
SCHEMBL4394729 0.90 KEAP1 (0.55) TDP1MEN1GAAKMT2ACA12
SCHEMBL383580 0.89 KEAP1 (0.58) TDP1MEN1GAAKMT2ACA12
SCHEMBL5568963 0.87 TDP1 (0.59) TDP1MEN1GAAKMT2ACA12
SCHEMBL20438644 0.86 TDP1 (0.43) TDP1MEN1GAAKMT2ACA12
SCHEMBL3792515 0.85 TDP1 (0.42) TDP1MEN1GAAKMT2ACA12
SCHEMBL3788638 0.85 TDP1 (0.42) TDP1MEN1GAAKMT2ACA12
SCHEMBL1338814 0.84 TDP1 (0.50) TDP1MEN1GAAKMT2ACA12
SCHEMBL14115159 0.82 TDP1 (0.43) TDP1MEN1GAAKMT2ACA12
SCHEMBL7962147 0.78 TDP1 (0.55) TDP1MEN1GAAKMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 EP disclosed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
EP-3074010-B1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE INC (US) 2025-05-14 EP disclosed
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 US disclosed
US-20250057960-A1 OLIGOSACCHARIDE COMPLEXES AND USES BioNTech SE (DE) 2025-02-20 US disclosed
US-20250057944-A1 OLIGOSACCHARIDE COMPLEXES AND USES CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2025-02-20 US disclosed
WO-2025024883-A1 NOVEL BROAD SPECTRUM ANTIVIRAL AND ANTIMICROBIAL PEPTIDE MIMICS NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2025-02-06 WO disclosed
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2025-02-04 US disclosed
US-20250002522-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2025-01-02 US disclosed
US-20240425541-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES BioNTech SE (DE) 2024-12-26 US disclosed
US-6812218-B2 TRANSFERRING NUCLEIC ACIDS TO CELLS GENCELL S.A. (FR) 2004-11-02 US disclosed
EP-1390345-A1 POLYTHIOUREA LIPID DERIVATIVES GENCELL S.A. (FR) 2004-02-25 EP disclosed
US-20030087925-A1 Benzoamide piperidine containing compounds and related compounds PFIZER INC. 2003-05-08 US disclosed
US-20030065033-A1 Lipid derivatives of polythiourea GENCELL S.A. (FR) 2003-04-03 US disclosed
EP-1272484-A2 BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS Pfizer Products Inc. (US) 2003-01-08 EP disclosed
WO-2002092558-A1 POLYTHIOUREA LIPID DERIVATIVES GENCELL S.A. (FR) 2002-11-21 WO disclosed
US-6420558-B1 COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS MEIJI SEIKA KAISHA, LTD. (JP) 2002-07-16 US disclosed
WO-2001077100-A2 BENZOAMIDE PIPERIDINE COMPOUNDS AS SUBSTANCE P ANTAGONISTS PFIZER PRODUCTS INC. (US) 2001-10-18 WO disclosed
EP-1074543-A1 AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS MEIJI SEIKA KAISHA LTD. (JP) 2001-02-07 EP disclosed
US-5789406-A Indeno 1,2-E!pyrazine-4-ones, their preparation and the medicaments containing them RHONE-POULENC RORER S.A. (FR) 1998-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057944-A1 OLIGOSACCHARIDE COMPLEXES AND USES FUT6, NSUN3, OSTC TDP1 2485/4885MEN1 3002/4885GAA 254/4885
US-20250057960-A1 OLIGOSACCHARIDE COMPLEXES AND USES CD4, FUT6, UGCG TDP1 4398/4885MEN1 3067/4885GAA 307/4885
US-20030065033-A1 Lipid derivatives of polythiourea ABCB4, TENT4A, PEBP1 TDP1 547/4885MEN1 3623/4885GAA 1020/4885
US-20250002522-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES OSTC, FUT6, MAN2B2 TDP1 1306/4885MEN1 2389/4885GAA 40/4885
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A TDP1 1412/4885MEN1 903/4885GAA 1772/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 TDP1 4498/4885MEN1 4823/4885GAA 2425/4885
US-20240425541-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES OSTC, SNRPA, RNASE1 TDP1 1188/4885MEN1 1741/4885GAA 57/4885
US-20030087925-A1 Benzoamide piperidine containing compounds and related compounds TACR1, VIPR1, VIPR2 TDP1 2921/4885MEN1 2361/4885GAA 781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.