Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792440 | 0.88 | LMNA (0.41) | HINT1ALDH1A1HTTLMNAMTOR | |
| Hydrochloric Acid SCHEMBL11859227 | 0.87 | L3MBTL1 (0.45) | HINT1LMNAL3MBTL1 | |
| SCHEMBL17748441 | 0.86 | ADORA3 (0.53) | ALDH1A1HTTLMNAMTORTHRB | |
| SCHEMBL21998920 | 0.85 | ADK (0.52) | ALDH1A1HTTLMNAMTORTHRB | |
| SCHEMBL234387 | 0.85 | LMNA (0.46) | ALDH1A1HTTLMNAMTORTHRB | |
| SCHEMBL1684799 | 0.85 | ADK (0.52) | ALDH1A1HTTLMNAMTORTHRB | |
| SCHEMBL5038377 | 0.85 | ALDH1A1 (0.62) | HINT1ALDH1A1HTTLMNAMTOR | |
| SCHEMBL5955214 | 0.84 | ADORA3 (0.45) | ALDH1A1HTTLMNAMTORTHRB | |
| SCHEMBL24798428 | 0.84 | LMNA (0.45) | ALDH1A1HTTLMNAMTORTHRB | |
| SCHEMBL17210993 | 0.83 | P2RY2 (0.50) | P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408306-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | Alios Biopharma, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108140-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2010-09-23 | — | — | WO | disclosed |