Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.51 |
| ▸ | DRD3 | P35462 | 7/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383016 | 0.88 | DRD2 (0.55) | DRD2DRD3CNR1CNR2MAPK1 | |
| SCHEMBL383328 | 0.87 | DRD2 (0.51) | DRD2DRD3SYKMAPK1NPC1 | |
| SCHEMBL382510 | 0.81 | NOS2 (0.51) | DRD2DRD3MAPK1 | |
| SCHEMBL382583 | 0.81 | CASR (0.54) | DRD2DRD3CNR1CNR2 | |
| SCHEMBL383181 | 0.81 | CASR (0.54) | DRD2DRD3CNR1CNR2 | |
| SCHEMBL382964 | 0.79 | CASR (0.45) | DRD2DRD3 | |
| SCHEMBL28747046 | 0.79 | ITGB3 (0.49) | DRD2DRD3CNR1CNR2 | |
| SCHEMBL7539445 | 0.79 | CNR1 (0.44) | DRD2DRD3CNR1CNR2 | |
| SCHEMBL382962 | 0.79 | ITGB3 (0.49) | DRD2DRD3CNR1CNR2 | |
| SCHEMBL382518 | 0.78 | DRD2 (0.53) | DRD2DRD3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| CN-1303377-A | Amino piperidine derivatives as integrin alpha beta 3 antagonists | MEIJI SEIKA KAISHA (JP) | 2001-07-11 | — | — | CN | claimed |
| CN-1303377-A | Amino piperidine derivatives as integrin alpha beta 3 antagonists | MEIJI SEIKA KAISHA (JP) | 2001-07-11 | — | — | CN | disclosed |