Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.51 |
| ▸ | DRD3 | P35462 | 9/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383016 | 0.88 | DRD2 (0.55) | DRD2DRD3MAPK1NPC1RAB9A | |
| SCHEMBL383329 | 0.87 | DRD2 (0.51) | DRD2DRD3MAPK1NPC1RAB9A | |
| SCHEMBL382510 | 0.81 | NOS2 (0.51) | DRD2DRD3MAPK1KDM4EDGAT1 | |
| SCHEMBL383181 | 0.81 | CASR (0.54) | DRD2DRD3HDAC8HDAC6USP2 | |
| SCHEMBL382583 | 0.81 | CASR (0.54) | DRD2DRD3HDAC8HDAC6USP2 | |
| SCHEMBL382518 | 0.78 | DRD2 (0.53) | DRD2DRD3MAPK1KDM4EGAA | |
| SCHEMBL383037 | 0.78 | DRD2 (0.53) | DRD2DRD3MAPK1KDM4EGAA | |
| SCHEMBL27474182 | 0.77 | NAAA (0.50) | DRD3MAPK1HDAC8HDAC1ALDH1A1 | |
| SCHEMBL6796559 | 0.77 | CASR (0.45) | DRD2DRD3EPHX2HDAC1ME3 | |
| SCHEMBL6796554 | 0.77 | ITGB3 (0.49) | DRD2DRD3EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |