SCHEMBL3839716

SCHEMBL3839716

Cc1cccc(-c2cc(C)c3ccc(C)cc3n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
MAPT P10636 3/20 0.49
THRB P10828 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
XDH P47989 1/20 0.44
KDM4E B2RXH2 4/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 2/20 0.43
HSD17B10 Q99714 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
RECQL P46063 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PSMB5 P28074 1/20 0.43
IDO1 P14902 1/20 0.42
METAP2 P50579 1/20 0.42
CYP1A2 P05177 1/20 0.42
HSP90AA1 P07900 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4101472 0.89 PSMB5 (0.49) ALDH1A1MAPTTHRBTDP1XDH
SCHEMBL13541765 0.88 ALDH1A1 (0.55) ALDH1A1MAPTTHRBTDP1KDM4E
SCHEMBL20809335 0.87 ALDH1A1 (0.54) ALDH1A1MAPTTHRBTDP1XDH
SCHEMBL20809291 0.87 ALDH1A1 (0.63) ALDH1A1MAPTTHRBTDP1KDM4E
SCHEMBL13309775 0.86 PSMB5 (0.41) ALDH1A1MAPTTHRBTDP1KDM4E
SCHEMBL14500790 0.85 KDM4E (0.57) ALDH1A1MAPTTHRBTDP1KDM4E
SCHEMBL14500787 0.84 GRM2 (0.49) ALDH1A1MAPTTDP1KDM4EMEN1
SCHEMBL20809088 0.84 XDH (0.42) ALDH1A1MAPTTHRBXDHKDM4E
SCHEMBL14500785 0.83 NPC1 (0.47) ALDH1A1MAPTTHRBTDP1KDM4E
SCHEMBL14500792 0.81 KDM4E (0.59) ALDH1A1MAPTTDP1XDHKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed
US-9023489-B2 Red phosphorescent compounds and organic electroluminescent devices using the same LG DISPLAY CO., LTD. (KR) 2015-05-05 US disclosed
US-9023489-B2 Red phosphorescent compounds and organic electroluminescent devices using the same LG DISPLAY CO., LTD. (KR) 2015-05-05 US disclosed
US-9023489-B2 Red phosphorescent compounds and organic electroluminescent devices using the same LG DISPLAY CO., LTD. (KR) 2015-05-05 US disclosed
EP-1783132-B1 Red phosphorescent compounds and organic electromuninescent devices using the same LG DISPLAY CO LTD (KR) 2009-10-14 EP disclosed
EP-1783132-B1 Red phosphorescent compounds and organic electromuninescent devices using the same LG DISPLAY CO LTD (KR) 2009-10-14 EP disclosed
US-20070104980-A1 Red phosphorescent compounds and organic electroluminescent devices using the same LG DISPLAY CO., LTD. (KR) 2007-05-10 US disclosed
US-20070104980-A1 Red phosphorescent compounds and organic electroluminescent devices using the same LG DISPLAY CO., LTD. (KR) 2007-05-10 US disclosed
US-20070104980-A1 Red phosphorescent compounds and organic electroluminescent devices using the same LG DISPLAY CO., LTD. (KR) 2007-05-10 US disclosed
EP-1783132-A1 Red phosphorescent compounds and organic electromuninescent devices using the same LG Electronics Inc. (KR) 2007-05-09 EP disclosed
EP-1783132-A1 Red phosphorescent compounds and organic electromuninescent devices using the same LG Electronics Inc. (KR) 2007-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 ALDH1A1 42/4885MAPT 1714/4885THRB 3013/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 ALDH1A1 42/4885MAPT 1714/4885THRB 3013/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 ALDH1A1 16/4885MAPT 1579/4885THRB 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.