SCHEMBL4101472

SCHEMBL4101472

Cc1cccc(-c2ccc3c(C)cc(C)cc3n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 2/20 0.49
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
KMO O15229 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
IDO1 P14902 1/20 0.41
METAP2 P50579 1/20 0.41
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
XDH P47989 1/20 0.40
AR P10275 1/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
ENPP3 O14638 1/20 0.39
NR1I3 Q14994 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839716 0.89 ALDH1A1 (0.49) PSMB5BCHEACHEALDH1A1MAPT
SCHEMBL20809298 0.87 PSMB5 (0.59) PSMB5ACHEALDH1A1MAPTTHRB
SCHEMBL13870791 0.86 PSMB5 (0.46) PSMB5ACHEALDH1A1MAPTRAB9A
SCHEMBL20809054 0.85 BCHE (0.47) BCHEACHEKMOALDH1A1MAPT
SCHEMBL31058808 0.84 BCHE (0.46) BCHEACHEKMOALDH1A1MAPT
SCHEMBL29262959 0.84 BCHE (0.46) BCHEACHEKMOALDH1A1MAPT
SCHEMBL13870891 0.84 MAP4K4 (0.48) PSMB5ALDH1A1MAPTTDP1RAB9A
SCHEMBL27761556 0.83 NOS3 (0.61) PSMB5ALDH1A1MAPTTHRBTDP1
SCHEMBL13870900 0.83 BCHE (0.41) BCHEACHEKMOALDH1A1MAPT
SCHEMBL13870894 0.82 NPC1 (0.47) PSMB5ALDH1A1MAPTRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-10998507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-04 US disclosed
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed
US-20170148988-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-05-25 US disclosed
US-20170148988-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-05-25 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 PSMB5 4813/4885BCHE 2415/4885ACHE 37/4885
US-20170148988-A1 Organic Electroluminescent Materials and Devices CPNE4, MT-ND5, CENPE PSMB5 4606/4885BCHE 1100/4885ACHE 705/4885
US-11832456-B2 Organic electroluminescent materials and devices CPNE4, CYBA, EPCAM PSMB5 3637/4885BCHE 963/4885ACHE 339/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 PSMB5 4813/4885BCHE 2415/4885ACHE 37/4885
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 PSMB5 4884/4885BCHE 4245/4885ACHE 855/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 PSMB5 4831/4885BCHE 2661/4885ACHE 6/4885
US-10998507-B2 Organic electroluminescent materials and devices CPNE4, MT-ND5, CENPE PSMB5 4606/4885BCHE 1100/4885ACHE 705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.