SCHEMBL3841892

SCHEMBL3841892

C[C]=C(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.41
CES2 O00748 4/20 0.41
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
MAPT P10636 3/20 0.39
F2 P00734 2/20 0.38
CYP3A4 P08684 2/20 0.38
BLM P54132 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
F10 P00742 1/20 0.38
F12 P00748 1/20 0.38
F7 P08709 1/20 0.38
F3 P13726 1/20 0.38
PKM P14618 1/20 0.38
POLB P06746 1/20 0.38
PARP1 P09874 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2181511 0.75 ALDH1A1 (0.53) CES1CES2TSHRALDH1A1DAO
SCHEMBL7136968 0.75 CES1 (0.45) CES1CES2TSHRALDH1A1DAO
SCHEMBL701017 0.74 CES2 (0.44) CES1CES2TSHRALDH1A1DAO
SCHEMBL3846147 0.74 CES2 (0.44) CES1CES2TSHRALDH1A1DAO
SCHEMBL9194201 0.74 CES2 (0.44) CES1CES2TSHRALDH1A1DAO
SCHEMBL8946209 0.72 ALDH1A1 (0.43) CES1CES2TSHRALDH1A1DAO
SCHEMBL366630 0.71 CES1 (0.41) CES1CES2TSHRALDH1A1DAO
SCHEMBL3676537 0.71 CES1 (0.41) CES1CES2TSHRALDH1A1DAO
SCHEMBL80355 0.71 CES1 (0.48) CES1CES2TSHRALDH1A1DAO
SCHEMBL181161 0.71 CES1 (0.41) CES1CES2TSHRALDH1A1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624209-A Organic electroluminescent material and device 环球展览公司 2024-03-01 CN disclosed
CN-116891498-A Organic electroluminescent material and device 环球展览公司 2023-10-17 CN disclosed
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed
EP-1070110-B1 HYDRAULIC PROCESSES USING MICROGEL DISPERSION GOODRICH CORP (US) 2005-09-14 EP disclosed
US-6365776-B1 FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-04-02 US disclosed
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TAKASAGO INTERNATIONAL CORPORATION 2002-03-21 US disclosed
US-6237333-B1 Microgel disersion for hydraulic apparatus and processes THE B. F. GOODRICH COMPANY 2001-05-29 US disclosed
EP-1070110-A2 MICROGEL DISPERSION FOR HYDRAULIC APPARATUS AND PROCESSES THE B.F. GOODRICH COMPANY (US) 2001-01-24 EP disclosed
WO-1999051712-A2 MICROGEL DISPERSION FOR HYDRAULIC APPARATUS AND PROCESSES THE B.F. GOODRICH COMPANY (US) 1999-10-14 WO disclosed
US-4233216-A INTERMEDIATES FOR OXADETHIACEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1980-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TYR, DDC, PNMT CES1 4664/4885CES2 3385/4885TSHR 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.