Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136968 | 0.75 | CES1 (0.45) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL2181511 | 0.75 | ALDH1A1 (0.53) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11775078 | 0.71 | CES1 (0.41) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL366630 | 0.71 | CES1 (0.41) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL80355 | 0.71 | CES1 (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL3841892 | 0.71 | CES1 (0.41) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL28632577 | 0.69 | CES1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL170296 | 0.69 | ALDH1A1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL6935566 | 0.67 | CES1 (0.38) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL8946209 | 0.67 | ALDH1A1 (0.43) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864341-B1 | METHOD FOR PREPARATION OF A RUTHENIUM INDENYLIDENE COMPLEX | UMICORE AG & CO KG (DE) | 2018-09-26 | — | — | EP | disclosed |
| EP-2679593-B1 | Method for preparation of a ruthenium indenylidene complex | UMICORE AG & CO KG (DE) | 2018-03-21 | — | — | EP | disclosed |
| US-9604205-B2 | Method for preparation of a ruthenium indenylidene complex | UMICORE AG & CO. KG (DE) | 2017-03-28 | — | — | US | disclosed |
| US-20170043332-A1 | Method for Preparation of a Ruthenium Indenylidene Complex | UMICORE AG & CO KG (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20160228864-A1 | Method for Preparation of a Ruthenium Indenylidene Complex | UMICORE AG & CO KG (DE) | 2016-08-11 | — | — | US | disclosed |
| US-9339804-B2 | Method for preparation of a ruthenium indenylidene complex | UMICORE AG & CO. KG (DE) | 2016-05-17 | — | — | US | disclosed |
| US-20150190795-A1 | Method for Preparation of a Ruthenium Indenylidene Complex | UMICORE AG & CO. KG (DE) | 2015-07-09 | — | — | US | disclosed |
| EP-2864341-A1 | METHOD FOR PREPARATION OF A RUTHENIUM INDENYLIDENE COMPLEX | UMICORE AG & CO. KG (DE) | 2015-04-29 | — | — | EP | disclosed |
| EP-1904424-B1 | THE USE OF A PHOSPHORUS CONTAINING LIGAND AND A CYCLIC ORGANIC LIGAND IN A TRANSITION METAL COMPOUND | UMICORE AG & CO KG (DE) | 2014-12-10 | — | — | EP | disclosed |
| WO-2014001291-A1 | METHOD FOR PREPARATION OF A RUTHENIUM INDENYLIDENE COMPLEX | UMICORE AG & CO. KG (DE) | 2014-01-03 | — | — | WO | disclosed |
| US-7671224-B2 | Use of a phosphorus containing ligand and a cyclic organic ligand in a transition metal compound | UMICORE AG & CO. KG (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20080221345-A1 | Use of a Phosphorus Containing Ligand and a Cyclic Organic Ligand in a Transition Metal Compound | UMICORE AG & CO KG (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1904424-A2 | THE USE OF A PHOSPHORUS CONTAINING LIGAND AND A CYCLIC ORGANIC LIGAND IN A TRANSITION METAL COMPOUND | Sasol Technology (UK) Limited (GB) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010453-A2 | TRANSITION METAL COMPOUNDS HAVING A CYCLIC PHOSPHORUS-CONTAINING LIGAND AND A CYCLIC ORGANIC LIGAND FOR USE IN METATHESIS REACTIONS | SASOL TECHNOLOGY (UK) LIMITED (GB) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221345-A1 | Use of a Phosphorus Containing Ligand and a Cyclic Organic Ligand in a Transition Metal Compound | SOST, BMP2, LIG1 | CES1 4629/4885CES2 4548/4885TSHR 3347/4885 |
| US-20150190795-A1 | Method for Preparation of a Ruthenium Indenylidene Complex | RPL3, RPL13A, PRPF3 | CES1 3739/4885CES2 3942/4885TSHR 1962/4885 |
| US-20160228864-A1 | Method for Preparation of a Ruthenium Indenylidene Complex | RPL3, RPL13A, UPP1 | CES1 3441/4885CES2 3861/4885TSHR 1932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.