Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Nitrous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL6915974 | 1.00 | — | — | |
| Nitrous Acid SCHEMBL6914319 | 1.00 | ALDH1A1 (0.58) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL8089085 | 0.96 | — | — | |
| Nitrous Acid SCHEMBL28390565 | 0.96 | ALDH1A1 (0.64) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL2811655 | 0.96 | — | — | |
| Nitrous Acid SCHEMBL284904 | 0.92 | ALDH1A1 (0.58) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL30978284 | 0.92 | — | — | |
| Nitrous Acid SCHEMBL28104985 | 0.92 | ALDH1A1 (0.58) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL9174962 | 0.87 | — | — | |
| Nitrous Acid SCHEMBL28826783 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619099-B2 | Reduction of acrylic acid in the production of maleic anhydride | SCIENTIFIC DESIGN COMPANY, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-7589217-B2 | Yield improvement in the production of maleic anhydride | SD LIZENZVERWERTUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20070249848-A1 | Yield improvement in the production of maleic anhydride | SD LIZENZVERWERTUNGSGESELLSCHAFT MBH & CO. KG | 2007-10-25 | — | — | US | disclosed |
| US-20070244332-A1 | Reduction of acrylic acid in the production of maleic anhydride | SCIENTIFIC DESIGN COMPANY AND LONZA, S.P.A. | 2007-10-18 | — | — | US | disclosed |
| EP-1007206-B1 | PHOSPHORUS/VANADIUM CATALYST PREPARATION | SCIENT DESIGN CO (US) | 2004-11-17 | — | — | EP | disclosed |
| EP-1212310-B1 | PRODUCTION OF MALEIC ANHYDRIDE | SCIENT DESIGN CO (US) | 2004-09-22 | — | — | EP | disclosed |
| EP-1152826-A4 | PHOSPHORUS/VANADIUM MALEIC ANHYDRIDE CATALYST PREPARATION | SCIENT DESIGN CO (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1212310-A4 | PRODUCTION OF MALEIC ANHYDRIDE | SCIENT DESIGN CO (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1212310-A1 | PRODUCTION OF MALEIC ANHYDRIDE | Scientific Design Company Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1007206-A4 | PHOSPHORUS/VANADIUM CATALYST PREPARATION | SCIENT DESIGN CO (US) | 2002-05-15 | — | — | EP | disclosed |
| US-5280003-A | Reducing vanadium compound in concentrated phosphoric acid | SCIENTIFIC DESIGN COMPANY, INC. (US) | 1994-01-18 | — | — | US | disclosed |
| US-5262548-A | Oxidation of hydrocarbons to anhydrides | SCIENTIFIC DESIGN COMPANY, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5158923-A | Adding molybdenum to stabilize catalyst | SCIENTIFIC DESIGN COMPANY, INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0507617-A2 | Two stage process for producing maleic anhydride from butane | Scientific Design Company Inc. (US) | 1992-10-07 | — | — | EP | disclosed |
| US-5070060-A | OXIDATION OF BUTANE TO MALEIC ANHYDRIDE | SCIENTIFIC DESIGN COMPANY, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0458541-A1 | Improved phosphorous/vanadium oxidation catalyst | Scientific Design Company Inc. (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4596878-A | Vapor phase oxidation of hydrocarbons using vanadium, phosphorus, oxygen catalyst, heating catalyst with phosphorus compound to regenerate | DENKA CHEMICAL CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |
| US-4515899-A | REDISTRIBUTION OF PHOSPHORUS COMPOUND | DENKA CHEMICAL CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4283307-A | PHOSPHORUS-VANADIUM OXIDATION CATALYSTS | DENKA CHEMICAL CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4251390-A | MIXED OXIDES OF VANADIUM AND PHOSPHORUS WITH ZINC PROMOTER | DENKA CHEMICAL CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |