Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nitrous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL28390565 | 0.96 | ALDH1A1 (0.64) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL8089085 | 0.96 | — | — | |
| Nitrous Acid SCHEMBL30978284 | 0.92 | — | — | |
| Nitrous Acid SCHEMBL3851647 | 0.92 | ALDH1A1 (0.58) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL6915974 | 0.92 | — | — | |
| Nitrous Acid SCHEMBL28104985 | 0.92 | ALDH1A1 (0.58) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL6914319 | 0.92 | ALDH1A1 (0.58) | ALDH1A1ALOX15TDP1MEN1KMT2A | |
| Nitrous Acid SCHEMBL2811655 | 0.87 | — | — | |
| Nitrous Acid SCHEMBL9174962 | 0.87 | — | — | |
| Nitrous Acid SCHEMBL28817750 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118141862-A | Ginseng composition, preparation method and detection method thereof | 通化东圣药品药材有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-114486798-B | Method for rapidly predicting total flavone content in pteridium aquilinum | 皖西学院 | 2024-03-26 | — | — | CN | claimed |
| CN-111504997-B | Method for extracting components of corn stigma and straws and testing in-vitro hypoglycemic activity of components | 吉林鑫水科技开发有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-114878501-A | Ultraviolet spectrometry method for flavonoid compounds in epimedium herb | 永州市农业科学研究所 | 2022-08-09 | — | — | CN | claimed |
| CN-114486798-A | Method for rapidly predicting content of total flavonoids in fiddlehead | 皖西学院 | 2022-05-13 | — | — | CN | claimed |
| CN-111329897-B | Method for producing flavone by fermenting myrtle through mixed probiotics | 广西壮族自治区兽医研究所 | 2022-04-15 | — | — | CN | claimed |
| CN-109172676-B | Application of total flavone extract of prickly ash leaves | 中国科学院兰州化学物理研究所 | 2021-09-14 | — | — | CN | claimed |
| CN-109288914-B | Application of houttuynia cordata total flavonoids in preparation of medicine for preventing and treating viral pneumonia | 复旦大学 | 2021-09-07 | — | — | CN | claimed |
| CN-112168852-A | Ultrasonic extraction process of myrobalan total flavonoids | 内蒙古自治区农牧业科学院 | 2021-01-05 | — | — | CN | claimed |
| CN-112048529-A | Method for producing quercetin by using microbial fermentation technology | 延安制药股份有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-111504997-A | Method for extracting components of corn stigma and straws and testing in-vitro hypoglycemic activity of components | 吉林鑫水科技开发有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-111329897-A | Method for producing flavone by fermenting myrtle through mixed probiotics | 广西壮族自治区兽医研究所 | 2020-06-26 | — | — | CN | claimed |
| CN-111220784-A | Honey-roasted white mulberry root-bark and quality evaluation method | 山东省中医药研究院 | 2020-06-02 | — | — | CN | claimed |
| CN-105494092-B | The induction of radix tetrastigme adventitious root and propagation method | 杭州市农业科学研究院 | 2018-04-20 | — | — | CN | claimed |
| CN-104062257-B | A kind of based on the method for general flavone content near infrared ray solution | 山东东阿阿胶股份有限公司 | 2016-09-21 | — | — | CN | claimed |
| US-20080233242-A1 | Antioxidant of Bamboo Leaves and Its Uses | ZHANG YING | 2008-09-25 | — | — | US | claimed |
| CN-118340804-A | Processing method for improving content of cynomorium songaricum nutritional ingredients | 兰州大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-118203532-A | Momordica grosvenori fermentation liquor and preparation method, composition and application thereof | 上海瑞帝安生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-101085072-A | Sustained-release tablet containing folium crataegi total flavone | UNIV FUDAN (CN) | 2007-12-12 | — | — | CN | disclosed |
| CN-101069707-A | Herba polygonic avicularis total flavones and its preparing method and medicine use | GUO WEIYING (CN) | 2007-11-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233242-A1 | Antioxidant of Bamboo Leaves and Its Uses | LPO, DBI, CAT | ALDH1A1 1464/4885ALOX15 15/4885TDP1 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.