Nitrous Acid

Nitrous Acid

SCHEMBL8089085

O=N[O-].O=[N+]([O-])[O-].[Na+].[Na+]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Nitrous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrous Acid SCHEMBL28390565 1.00 ALDH1A1 (0.64)
Nitrous Acid SCHEMBL30978284 0.96
Nitrous Acid SCHEMBL6915974 0.96
Nitrous Acid SCHEMBL3851647 0.96 ALDH1A1 (0.58)
Nitrous Acid SCHEMBL6914319 0.96 ALDH1A1 (0.58)
Nitrous Acid SCHEMBL284904 0.96 ALDH1A1 (0.58)
Nitrous Acid SCHEMBL28104985 0.96 ALDH1A1 (0.58)
Nitrous Acid SCHEMBL2811655 0.91
Nitrous Acid SCHEMBL28826783 0.91
Nitrous Acid SCHEMBL28817750 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108355717-A A kind of preparation method of cellulose/BiOBr composite photocatalyst materials 齐鲁工业大学 2018-08-03 CN claimed
US-20160240101-A1 Nutritional Value Of Food SPINS LLC 2016-08-18 US disclosed
US-20140121191-A1 Oral Energy Supplement and Related Methods HUDSON BAY MASTER FUND LTD. 2014-05-01 US disclosed
US-8309157-B2 Meat-containing, strip-shaped food product and method of making same DEL MONTE CORPORATION (US) 2012-11-13 US disclosed
US-6089479-A Method for treating waste printed circuit boards with molten mixture of inorganic salts Cleanenv' Engineeering Consultant Co., Ltd. (TW) 2000-07-18 US disclosed
US-4629503-A Process for the recovery of tungsten in a pure form from tungsten-containing materials RAMOT - UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT (IL) 1986-12-16 US disclosed
EP-0148924-A1 HYDROGEN SELENIDE TREATMENT OF ELECTROLYTES CERAMATEC, INC. (US) 1985-07-24 EP disclosed
WO-1985000470-A1 HYDROGEN SELENIDE TREATMENT OF ELECTROLYTES CERAMATEC, INC. (US) 1985-01-31 WO disclosed
US-4197161-A TRANSITION METAL COMPOUNDS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-04-08 US disclosed
US-4113885-A CURING SOLUTION CONTAINING POTASSIUM NITRITE, AMMONIUM NITRITE, OR NITROUS ACID ZYSS THADEUS B 1978-09-12 US disclosed
US-3966974-A LESS PRODUCTION OF NITROSAMINES CANADA PACKERS LIMITED (CA) 1976-06-29 US disclosed