SCHEMBL3853933

SCHEMBL3853933

C=C[C](c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
TSHR P16473 2/20 0.44
MAPK1 P28482 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALOX15 P16050 1/20 0.44
CYP3A4 P08684 1/20 0.44
ATM Q13315 1/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
LMNA P02545 3/20 0.42
CYP2A6 P11509 1/20 0.42
GSK3B P49841 2/20 0.39
SRD5A2 P31213 1/20 0.39
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17513783 0.84 HPGD (0.59) CES2CES1TSHRMAPK1LMNA
SCHEMBL52041 0.77 CES2 (0.44) CES2CES1TSHRMAPK1L3MBTL1
SCHEMBL7190703 0.76 ALDH5A1 (0.58) TSHRMAPK1ALOX15CYP3A4CA1
SCHEMBL23416837 0.75 LMNA (0.48) CES2CES1TSHRMAPK1L3MBTL1
SCHEMBL1224122 0.75 ALDH5A1 (0.64) CES2CES1TSHRMAPK1ALOX15
SCHEMBL11496633 0.74 ALDH1A1 (0.46) CES2CES1ATMLMNAGSK3B
SCHEMBL12786451 0.73 CES2 (0.41) CES2CES1TSHRMAPK1L3MBTL1
SCHEMBL21689751 0.73 CES2 (0.41) CES2CES1TSHRMAPK1L3MBTL1
SCHEMBL9422531 0.72 AKT1 (0.56) CES2CES1TSHRMAPK1L3MBTL1
SCHEMBL84200 0.72 AKT1 (0.56) CES2CES1TSHRMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116527-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, METHOD FOR PRODUCTION OF THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM Corporation (JP) 2009-11-11 EP disclosed
US-20030129504-A1 Photosensitive resin compositon, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. 2003-07-10 US disclosed