Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554371 | 0.78 | TSHR (0.39) | LMNA | |
| SCHEMBL1554380 | 0.78 | TSHR (0.39) | LMNA | |
| SCHEMBL1554300 | 0.78 | TSHR (0.39) | LMNA | |
| SCHEMBL1050419 | 0.78 | TSHR (0.44) | LMNA | |
| SCHEMBL30469491 | 0.78 | TSHR (0.44) | LMNA | |
| SCHEMBL19750288 | 0.76 | LMNA (0.35) | LMNA | |
| SCHEMBL19750289 | 0.76 | LMNA (0.35) | LMNA | |
| SCHEMBL30469492 | 0.75 | TSHR (0.45) | — | |
| SCHEMBL3187513 | 0.75 | TSHR (0.45) | — | |
| SCHEMBL1164512 | 0.74 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626034-B2 | Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-12-01 | — | — | US | disclosed |
| EP-2100875-A1 | Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives | Takasago International Corporation (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-7351849-B2 | Process for producing optically active β-amino acid derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20070142443-A1 | Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20060205968-A1 | Process for producing optically active beta-amino acid derivatives | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1656342-A2 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-AMINO ACID DERIVATIVES | Takasago International Corporation (JP) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005016866-A2 | PROCESS FOR PRODUCING OPTICALLY ACTIIVE BETA-AMINO ACID DERIVATIVES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205968-A1 | Process for producing optically active beta-amino acid derivatives | BCAT1, ALAD, AADAT | LMNA 1329/4885 |
| US-20070142443-A1 | Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives | AADAT, BCAT2, BCAT1 | LMNA 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.