Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970620 | 0.79 | AHR (0.50) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL29992449 | 0.79 | MEN1 (0.71) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL2426021 | 0.79 | AHR (0.55) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL74720 | 0.79 | MEN1 (0.71) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL4952881 | 0.79 | AHR (0.55) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL25462527 | 0.79 | AHR (0.50) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL1196876 | 0.79 | ABL1 (0.52) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL593378 | 0.79 | AHR (0.50) | AHRNR4A2LTA4HCYP2A6F7 | |
| SCHEMBL417223 | 0.78 | AHR (0.48) | AHRNR4A2LTA4HCYP2A6F7 | |
| Ammonia Solution, Strong SCHEMBL28589598 | 0.78 | MEN1 (0.69) | AHRNR4A2LTA4HCYP2A6F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612389-B2 | Benzofuran-based N-acylhydrazone derivative and pharmaceutical composition comprising same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2026-04-28 | — | — | US | disclosed |
| US-20230293487-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2023-09-21 | — | — | US | disclosed |
| EP-4186503-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | Korea Research Institute of Bioscience and Biotechnology (KR) | 2023-05-31 | — | — | EP | disclosed |
| US-20220306612-A1 | BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTEHNOLOGY (KR) | 2022-09-29 | — | — | US | disclosed |
| EP-4015516-A1 | BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Research Institute of Bioscience and Biotechnology (KR) | 2022-06-22 | — | — | EP | disclosed |
| CN-114206857-A | Benzofuranyl N-acylhydrazone derivatives and pharmaceutical compositions containing the same | 韩国生命工学研究院 | 2022-03-18 | — | — | CN | disclosed |
| WO-2022019663-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | 한국생명공학연구원 | 2022-01-27 | — | — | WO | disclosed |
| JP-2009040790-A | PROCESS FOR PREPARING 5-FLUOROOXYINDOLE | UBE IND LTD | 2009-02-26 | — | — | JP | disclosed |
| EP-1310486-A4 | PROCESS FOR PRODUCING 5-FLUOROOXYINDOLE AND FOR PRODUCING INTERMEDIATE THEREFOR | UBE INDUSTRIES (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-20030181731-A1 | Process for producing 5-fluorooxyindole and for producing intermediates therefor | UBE INDUSTRIES., LTD (JP) | 2003-09-25 | — | — | US | disclosed |
| JP-2002128761-A | METHOD FOR PRODUCING 5-FLUOROOXYINDOLE | UBE IND LTD | 2002-05-09 | — | — | JP | disclosed |
| WO-2002006228-A1 | PROCESS FOR PRODUCING 5-FLUOROOXYINDOLE AND FOR PRODUCING INTERMEDIATE THEREFOR | UBE INDUSTRIES, LTD. (JP) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306612-A1 | BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | NDUFAB1, BPTF, HDAC6 | AHR 151/4885NR4A2 687/4885LTA4H 3178/4885 |
| US-20230293487-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | RELA, NFKBIA, IKBKG | AHR 244/4885NR4A2 155/4885LTA4H 1247/4885 |
| US-12612389-B2 | Benzofuran-based N-acylhydrazone derivative and pharmaceutical composition comprising same | TUBB3, TUBA1C, ACIN1 | AHR 811/4885NR4A2 1886/4885LTA4H 4418/4885 |
| US-20030181731-A1 | Process for producing 5-fluorooxyindole and for producing intermediates therefor | FAR1, CYP4F11, FDPS | AHR 476/4885NR4A2 2594/4885LTA4H 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.