Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL3889766 | 0.81 | GPR84 (0.41) | CA2SLC1A2SLC1A1TSHRGRIK1 | |
| Glycinebetaine SCHEMBL1065800 | 0.81 | GPR84 (0.41) | CA2SLC1A2SLC1A1TSHRGRIK1 | |
| Glycinebetaine SCHEMBL156318 | 0.81 | GPR84 (0.41) | CA2SLC1A2SLC1A1TSHRGRIK1 | |
| Glycinebetaine SCHEMBL2135218 | 0.81 | GPR84 (0.41) | CA2SLC1A2SLC1A1TSHRGRIK1 | |
| Glycinebetaine SCHEMBL2132643 | 0.81 | GPR84 (0.41) | CA2SLC1A2SLC1A1TSHRGRIK1 | |
| Glycinebetaine SCHEMBL2131138 | 0.81 | GPR84 (0.41) | CA2SLC1A2SLC1A1TSHRGRIK1 | |
| Glycinebetaine SCHEMBL2133338 | 0.81 | GPR84 (0.41) | CA2SLC1A2SLC1A1TSHRGRIK1 | |
| Glycinebetaine SCHEMBL6416801 | 0.81 | ACE2 (0.43) | CA2SLC1A2SLC1A1CYP3A4TSHR | |
| Glycinebetaine SCHEMBL1893593 | 0.80 | CHRM1 (0.39) | SLC1A2SLC1A1SLC1A3ALDH1A1CYP3A4 | |
| Glycinebetaine SCHEMBL6417583 | 0.78 | CA2 (0.50) | CA2MAPK1SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216559-B2 | Deodorant fiber and fibrous article and product made thereof | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-7501390-B2 | Concentrated neutral detergent composition comprising an alkanesulfonic acid salt, a polyoxyalkylene alkyle ether, an alkyl polyglucoside, and water | JOHNSONDIVERSEY, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| EP-1725639-B1 | CONCENTRATED NEUTRAL DETERGENT COMPOSITION | JOHNSON DIVERSEY INC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20070287649-A1 | Concentrated Neutral Detergent Composition | DIVERSEY, INC. (FORMERLY KNOWN AS JOHNSONDIVERSEY, INC.) | 2007-12-13 | — | — | US | disclosed |
| EP-1725639-A1 | CONCENTRATED NEUTRAL DETERGENT COMPOSITION | JohnsonDiversey, Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| US-20050255078-A1 | Deodorant fiber and fibrous article and product made thereof | CHISSO CORPOARTION (JP) | 2005-11-17 | — | — | US | disclosed |
| WO-2005093028-A1 | CONCENTRATED NEUTRAL DETERGENT COMPOSITION | JOHNSONDIVERSEY, INC. (US) | 2005-10-06 | — | — | WO | disclosed |