Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 10/20 | 0.35 |
| ▸ | FNTB | P49356 | 10/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762279 | 1.00 | MAPT (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL332020 | 1.00 | MAPT (0.52) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Cysteine SCHEMBL20817549 | 0.90 | PTGS1 (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL11856516 | 0.85 | FNTA (0.51) | MAPTFNTAFNTBALDH1A1 | |
| SCHEMBL3863272 | 0.85 | FNTA (0.51) | MAPTFNTAFNTBALDH1A1 | |
| SCHEMBL3860439 | 0.85 | FNTA (0.51) | MAPTFNTAFNTBALDH1A1 | |
| SCHEMBL3863270 | 0.85 | FNTA (0.51) | MAPTFNTAFNTBALDH1A1 | |
| SCHEMBL20657039 | 0.84 | FNTA (0.54) | MAPTFNTAFNTBALDH1A1 | |
| SCHEMBL20535484 | 0.84 | FNTA (0.54) | MAPTFNTAFNTBALDH1A1 | |
| SCHEMBL1529433 | 0.84 | FNTA (0.54) | MAPTFNTAFNTBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137643-A1 | COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL | SOC DES PRODUITS NESTLE S A (CH) | 2026-05-21 | — | — | US | claimed |
| US-12539288-B2 | Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2026-02-03 | — | — | US | claimed |
| US-20250281438-A1 | COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2025-09-11 | — | — | US | claimed |
| US-11834430-B2 | Compounds useful as inhibitors of isoprenylcysteine carboxyl methyltransferase | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-12-05 | — | — | US | claimed |
| EP-4262776-A1 | COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL | Société des Produits Nestlé S.A. (CH) | 2023-10-25 | — | — | EP | claimed |
| WO-2022128870-A1 | COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL | Société des Produits Nestlé S.A. (CH) | 2022-06-23 | — | — | WO | claimed |
| US-20210130317-A1 | Compounds Useful as Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-05-06 | — | — | US | claimed |
| EP-3681878-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE | Agency for Science, Technology and Research (SG) | 2020-07-22 | — | — | EP | claimed |
| WO-2019054944-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-03-21 | — | — | WO | claimed |
| WO-2018101930-A1 | SKIN CARE COMPOSITION HAVING SKIN PROTECTION AND DAMAGE REPAIRING PROPERTIES | CGTN C.V. (US) | 2018-06-07 | — | — | WO | claimed |
| EP-1534842-A2 | STRESS TOLERANCE AND DELAYED SENESCENCE IN PLANTS | Performance Plants, Inc. (CA) | 2005-06-01 | — | — | EP | claimed |
| WO-2004020642-A2 | STRESS TOLERANCE AND DELAYED SENESCENCE IN PLANTS | PERFORMANCE PLANTS, INC. (CA) | 2004-03-11 | — | — | WO | claimed |
| US-20040010821-A1 | Stress tolerance and delayed senescence in plants | PERFORMANCE PLANTS INC. (CA) | 2004-01-15 | — | — | US | claimed |
| US-20030228688-A1 | Antisense modulation of isoprenylcysteine carboxyl methyltransferase expression | ISIS PHARMACEUTICALS INC. | 2003-12-11 | — | — | US | claimed |
| WO-2002072811-A2 | HUMAN PRENYLCYSTEINE LYASE-LIKE PROTEIN | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-19 | — | — | WO | claimed |
| US-6372793-B1 | NERVOUS SYSTEM DISORDERS, METHYLATION DEMETHYLATION FOR NEUROMODULATOR FUNCTIONS | FLORIDA AGRICULTURAL & MECHANICAL UNIVERSITY | 2002-04-16 | — | — | US | claimed |
| US-6232108-B1 | RECOMBINANT DNA CODING FOR ENZYME OF DEFINED AMINO ACID SEQUENCE WHICH IS INVOLVED IN FURTHER POST-TRANSLATIONAL PROCESSING OF PRENYLATED PROTEINS; DRUG SCREENING OF ANTICARCINOGENIC AND ANTINFLAMMATORY AGENTS | NEW YORK UNIVERSITY | 2001-05-15 | — | — | US | claimed |
| US-6184016-B1 | AMINO ACID SEQUENCE OF ENZYME INVOLVED IN POST-TRANSLATIONAL MODIFICATION OF PRENYLATED PROTEINS; FOR SCREENING OF ENZYME INHIBITORS; ANTIINFLAMMATORY/ANTICARCINOGENIC AGENTS | NEW YORK UNIVERSITY | 2001-02-06 | — | — | US | claimed |
| EP-1009833-A1 | PRENYLCYSTEINE CARBOXYL METHYL-TRANSFERASE, DNA ENCONDING SAME, AND A METHOD OF SCREENING FOR INHIBITORS THEREOF | NEW YORK UNIVERSITY (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1998056924-A1 | PRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE, DNA ENCODING SAME, AND A METHOD OF SCREENING FOR INHIBITORS THEREOF | NEW YORK UNIVERSITY (US) | 1998-12-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130317-A1 | Compounds Useful as Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase | ICMT, INMT, BHMT | MAPT 61/4885KDM4E 2117/4885THRB 1537/4885 |
| US-11834430-B2 | Compounds useful as inhibitors of isoprenylcysteine carboxyl methyltransferase | ICMT, INMT, BHMT | MAPT 61/4885KDM4E 2117/4885THRB 1537/4885 |
| US-12539288-B2 | Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol | LIPC, GGT1, TGM2 | MAPT 2353/4885KDM4E 4540/4885THRB 585/4885 |
| US-20260137643-A1 | COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL | LIPC, GGT1, TGM2 | MAPT 2204/4885KDM4E 4438/4885THRB 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.