Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid Monododecyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.59 |
| ▸ | AKT1 | P31749 | 2/20 | 0.56 |
| ▸ | CDC25A | P30304 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monodecyl Ester SCHEMBL28359660 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28359607 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL5680624 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28355333 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL3784849 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL483790 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL11255117 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28359340 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28359276 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Phosphoric Acid Monotetradecyl Ester SCHEMBL28355509 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119913663-A | Non-woven fabric for polylactic acid-polycaprolactone degradable woven bag and preparation method thereof | 温州新奥达塑业有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-103289806-A | Scratch-proof wire drawing oil | JIANGSU HAIAN PETROCHEMICAL PLANT | 2013-09-11 | — | — | CN | claimed |
| US-4707292-A | ANIONIC SURFACTANTS, SHAMPOO | KAO CORPORATION (JP) | 1987-11-17 | — | — | US | claimed |
| CN-122005622-A | Composition for improving, preventing or treating vaginitis or vulvitis comprising lactobacillus salivarius HHuMin-U | 比菲德股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12357553-B2 | Composition for treating hair loss or promoting hair growth, comprising piperonylic acid | Hesed Bio Co., Ltd. (KR) | 2025-07-15 | — | — | US | disclosed |
| CN-119913663-A | Non-woven fabric for polylactic acid-polycaprolactone degradable woven bag and preparation method thereof | 温州新奥达塑业有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119913663-A | Non-woven fabric for polylactic acid-polycaprolactone degradable woven bag and preparation method thereof | 温州新奥达塑业有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-115337242-B | Traditional Chinese medicine composition, extract, preparation method and application thereof, cosmetics and medicines | 上海如妍化妆品有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20250025523-A1 | COMPOSITION FOR PREVENTING OR TREATING MUSCLE DISEASE COMPRISING SARGASSUM SERRATIFOLIUM EXTRACT | Pukyong National University Industry- University Cooperation Foundation (KR) | 2025-01-23 | — | — | US | disclosed |
| EP-3662907-B1 | ANTI-AGING OR SKIN-REGENERATING COMPOSITION COMPRISING PIPERONYLIC ACID AS EFFECTIVE INGREDIENT | HESED BIO CO LTD (KR) | 2024-04-17 | — | — | EP | disclosed |
| CN-111315377-B | Anti-aging or skin regenerating composition containing pyrrole acid as active ingredient | 赫赛德生物有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20020009472-A1 | Cosmetics | KYOWA HAKKO BIO CO., LTD. (JP) | 2002-01-24 | — | — | US | disclosed |
| EP-1166767-A2 | Skin care product containing hydroxyproline or N-acylated hydroxyproline derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
| CN-1328813-A | Cosmetics | KYOWA HAKKO KOGY CO LTD (JP) | 2002-01-02 | — | — | CN | disclosed |
| EP-1159952-A1 | COSMETICS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-0321786-B1 | COMPOSITION FOR EXTERNAL APPLICATION | KAO CORPORATION (JP) | 1993-05-19 | — | — | EP | disclosed |
| EP-0321786-A2 | Composition for external application | KAO CORPORATION (JP) | 1989-06-28 | — | — | EP | disclosed |
| US-4707292-A | ANIONIC SURFACTANTS, SHAMPOO | KAO CORPORATION (JP) | 1987-11-17 | — | — | US | disclosed |
| US-4163018-A | REACTING AN ALKYL PHOSPHATE WITH A GROUP 2A, ZINC, OR ALUMINUM HALIDE, NITRATE, OR SULFATE | SAKAI CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1979-07-31 | — | — | US | disclosed |
| US-4115209-A | POLYMERIC MATRIX, CONDUCTIVE SUBSTRATE | RESEARCH CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12357553-B2 | Composition for treating hair loss or promoting hair growth, comprising piperonylic acid | EGFR, PDGFA, HGF | LPAR3 378/4885LPAR2 301/4885LPAR1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.