Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hexadecyl Dihydrogen Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.59 |
| ▸ | AKT1 | P31749 | 2/20 | 0.56 |
| ▸ | CDC25A | P30304 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monodecyl Ester SCHEMBL28359660 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28359607 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Hexadecyl Dihydrogen Phosphate SCHEMBL5680624 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28355333 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL3784849 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Phosphoric Acid Monododecyl Ester SCHEMBL3893034 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL11255117 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28359340 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| SCHEMBL28359276 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A | |
| Phosphoric Acid Monotetradecyl Ester SCHEMBL28355509 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1AKT1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2484336-B1 | PIGMENT FOR COSMETIC PREPARATIONS, METHOD FOR PRODUCING SAME, AND COSMETIC PREPARATION CONTAINING THE PIGMENT FOR COSMETIC PREPARATIONS | TOYO BOSEKI (JP) | 2021-01-20 | — | — | EP | claimed |
| US-9181436-B2 | Cosmetic pigments, their production method, and cosmetics containing the cosmetic pigments | TOYOBO CO., LTD. (JP) | 2015-11-10 | — | — | US | claimed |
| EP-4122443-B1 | COSMETIC COMPOSITION WITH SILICONE-MODIFIED POLYSACCHARIDE | SHINETSU CHEMICAL CO (JP) | 2026-05-06 | — | — | EP | disclosed |
| US-20260078211-A1 | A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE | DOW TORAY CO LTD (JP) | 2026-03-19 | — | — | US | disclosed |
| US-12559611-B2 | Hydrophobic alginic acid particle group and method for producing same | NISSHINBO HOLDINGS INC. (JP) | 2026-02-24 | — | — | US | disclosed |
| US-12539266-B2 | Cosmetic composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-03 | — | — | US | disclosed |
| US-12540217-B2 | Catechol functional organopolysiloxane, method for producing same, and powder treatment agent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-02-03 | — | — | US | disclosed |
| US-20260027032-A1 | HAIR IMPROVER AND HAIR IMPROVING COMPOSITION | Refine Holdings Co., Ltd. (JP) | 2026-01-29 | — | — | US | disclosed |
| EP-3838249-B1 | OIL-IN-WATER EMULSION COSMETIC COMPOSITION CONTAINING A CARBOXYLIC ACID MODIFIED SILICONE | DOW TORAY CO LTD (JP) | 2026-01-07 | — | — | EP | disclosed |
| EP-3838257-B1 | COSMETIC CONTAINING A CARBOXYLIC ACID MODIFIED SILICONE | DOW TORAY CO LTD (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12502345-B2 | Cosmetic | DOW TORAY CO., LTD. (JP) | 2025-12-23 | — | — | US | disclosed |
| EP-0321786-A2 | Composition for external application | KAO CORPORATION (JP) | 1989-06-28 | — | — | EP | disclosed |
| US-4446061-A | FIREPROOFING, SMOKELESS, PHOSPHITE/PHOSPHONATE | MONSANTO COMPANY (US) | 1984-05-01 | — | — | US | disclosed |
| US-4313761-A | FIREPROOFING AND SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4260542-A | FLAME RETARDANTS, SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4206133-A | FLAME RETARDANTS AND SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1980-06-03 | — | — | US | disclosed |
| US-4169859-A | POLYMERIC KETONE FROM ALPHA-OLEFIN AND ACYL HALIDE CATALYST, ASHLESS DETERGENTS | ATLANTIC RICHFIELD COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4157339-A | Phosphonamidic condensation reaction product | ATLANTIC RICHFIELD COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4133823-A | FIREPROOFING, SMOKELESS | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4028414-A | LUBE OIL DETERGENT | ATLANTIC RICHFIELD COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078211-A1 | A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE | FOXM1, FOXK1, TAF1L | LPAR3 2203/4885LPAR2 1876/4885LPAR1 1237/4885 |
| US-12539266-B2 | Cosmetic composition | CUTA, FSCN1, FUCA1 | LPAR3 1776/4885LPAR2 2065/4885LPAR1 1544/4885 |
| US-12540217-B2 | Catechol functional organopolysiloxane, method for producing same, and powder treatment agent | FANCD2, TYR, COL2A1 | LPAR3 2575/4885LPAR2 1380/4885LPAR1 1423/4885 |
| US-20260027032-A1 | HAIR IMPROVER AND HAIR IMPROVING COMPOSITION | KRT18, CUTA, DPM1 | LPAR3 3119/4885LPAR2 3313/4885LPAR1 2532/4885 |
| US-12559611-B2 | Hydrophobic alginic acid particle group and method for producing same | ALG3, ALG1, HACD3 | LPAR3 365/4885LPAR2 319/4885LPAR1 564/4885 |
| US-12502345-B2 | Cosmetic | CUTA, LIPA, PLIN5 | LPAR3 973/4885LPAR2 627/4885LPAR1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.