Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894625 | 0.92 | ALDH1A1 (0.50) | GSK3BL3MBTL1 | |
| SCHEMBL3900534 | 0.88 | MMP3 (0.49) | GSK3BL3MBTL1 | |
| SCHEMBL14131971 | 0.88 | GSK3B (0.50) | KMT2AHTTSMN1; SMN2GSK3BL3MBTL1 | |
| SCHEMBL3911504 | 0.85 | THRA (0.46) | GSK3BL3MBTL1 | |
| SCHEMBL3898501 | 0.84 | FFAR1 (0.54) | SMN1; SMN2 | |
| SCHEMBL3901407 | 0.80 | NPC1 (0.60) | KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4839630 | 0.80 | FFAR1 (0.53) | SMN1; SMN2 | |
| SCHEMBL3910475 | 0.79 | MMP2 (0.63) | SMN1; SMN2GSK3BL3MBTL1 | |
| SCHEMBL8605642 | 0.79 | PKM (0.69) | PKMHTTL3MBTL1PLA2G4B | |
| SCHEMBL4841724 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |