Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894625 | 0.96 | ALDH1A1 (0.50) | MMP3ALDH1A1MAPTGSK3BL3MBTL1 | |
| SCHEMBL14131971 | 0.92 | GSK3B (0.50) | MAPTHDAC1HDAC2GSK3BL3MBTL1 | |
| SCHEMBL3899346 | 0.88 | PKM (0.50) | GSK3BL3MBTL1 | |
| SCHEMBL3911504 | 0.84 | THRA (0.46) | ALDH1A1MAPTGSK3BL3MBTL1THRA | |
| SCHEMBL4839630 | 0.83 | FFAR1 (0.53) | MMP2 | |
| SCHEMBL4932550 | 0.80 | MMP3 (0.47) | MMP3HDAC1HDAC2SMPD1 | |
| SCHEMBL7388461 | 0.80 | TBXAS1 (0.56) | HRH1 | |
| SCHEMBL1780120 | 0.80 | MAPT (0.56) | MMP3ALDH1A1MAPTHDAC1HDAC2 | |
| SCHEMBL3902858 | 0.80 | RAB9A (0.58) | MAPTSMPD1RAB9A | |
| SCHEMBL3898501 | 0.79 | FFAR1 (0.54) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |