Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16693044 | 1.00 | CYP2A6 (0.58) | CYP2A6KDM4EALDH1A1L3MBTL1MGLL | |
| SCHEMBL7416778 | 0.78 | CYP2A6 (0.64) | CYP2A6MGLLGSK3BBCL2L1TUBB4A | |
| SCHEMBL16693155 | 0.77 | GFER (0.35) | CYP2A6KDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL16693089 | 0.77 | TUBB4A (0.46) | CYP2A6ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL2902480 | 0.75 | CYP2A6 (0.67) | CYP2A6MGLLGSK3BBCL2L1TUBB4A | |
| SCHEMBL11977426 | 0.74 | CYP2A6 (0.50) | CYP2A6KDM4EALDH1A1MGLLNPC1 | |
| SCHEMBL29629031 | 0.74 | CYP2A6 (1.00) | CYP2A6MGLLGSK3BBCL2L1TUBB4A | |
| SCHEMBL7079637 | 0.74 | CYP2A6 (0.64) | CYP2A6MGLLGSK3BBCL2L1TUBB4A | |
| SCHEMBL8996544 | 0.74 | CYP2A6 (0.64) | CYP2A6MGLLGSK3BBCL2L1TUBB4A | |
| SCHEMBL1567214 | 0.74 | CYP2A6 (0.64) | CYP2A6MGLLGSK3BBCL2L1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246795-B | Isoxazoline compound containing ether structure at 4-phenyl para-position, preparation method thereof and application thereof as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-115246795-A | Isoxazoline compound with 4-phenyl para-position containing ether structure, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| EP-1660464-B1 | CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING | LG LIFE SCIENCES LTD (KR) | 2015-02-25 | — | — | EP | disclosed |
| CN-1842521-B | Caspase inhibitors containing isoxazoline ring | LG LIFE SCIENCES LTD | 2012-09-05 | — | — | CN | disclosed |
| US-7557133-B2 | Caspase inhibitors containing isoxazoline ring | LG LIFE SCIENCES LTD. (KR) | 2009-07-07 | — | — | US | disclosed |
| EP-1660464-A4 | CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING | LG LIFE SCIENCES LTD (KR) | 2008-11-26 | — | — | EP | disclosed |
| US-20060223848-A1 | Caspase inhibitors containing isoxazoline ring | LG CHEM, LTD. (KR) | 2006-10-05 | — | — | US | disclosed |
| CN-1842521-A | Caspase inhibitors containing isoxazoline ring | LG LIFE SCIENCES LTD (KR) | 2006-10-04 | — | — | CN | disclosed |
| EP-1660464-A1 | CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING | LG Life Sciences Ltd. (KR) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021516-A1 | CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING | LG LIFE SCIENCES LTD. (KR) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223848-A1 | Caspase inhibitors containing isoxazoline ring | CASP1, CASP7, CASP2 | CYP2A6 2621/4885KDM4E 2139/4885ALDH1A1 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.